Artigo Acesso aberto Revisado por pares

A Hyaluronic Acid Demilune Scaffold and Polypyrrole-Coated Fibers Carrying Embedded Human Neural Precursor Cells and Curcumin for Surface Capping of Spinal Cord Injuries

2021; Multidisciplinary Digital Publishing Institute; Volume: 9; Issue: 12 Linguagem: Inglês

10.3390/biomedicines9121928

ISSN

2227-9059

Autores

Hoda Elkhenany, Pablo Bonilla, Esther Giraldo, Ana Alastrue‐Agudo, Michael J. Edel, Marı́a J. Vicent, Fernando Gisbert Roca, Cristina Martínez‐Ramos, Laura Rodríguez Doblado, Manuel Monleón Pradas, Victoria Moreno‐Manzano,

Tópico(s)

RNA Interference and Gene Delivery

Resumo

Tissue engineering, including cell transplantation and the application of biomaterials and bioactive molecules, represents a promising approach for regeneration following spinal cord injury (SCI). We designed a combinatorial tissue-engineered approach for the minimally invasive treatment of SCI-a hyaluronic acid (HA)-based scaffold containing polypyrrole-coated fibers (PPY) combined with the RAD16-I self-assembling peptide hydrogel (Corning

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