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Point prevalence survey of antibiotic use in hospitals in Latin American countries

2021; Oxford University Press; Volume: 77; Issue: 3 Linguagem: Inglês

10.1093/jac/dkab459

1460-2091

Gabriel Levy Hara, Robin Rojas-Cortés, Helvert Felipe Molina León, Anahí Dreser, Ismary Alfonso Orta, José Noe Rizo-Amezquita, René Guillermo Santos Herrera, Silvia Mendoza de Ayala, Marlen Arce Villalobos, Hilda Mantilla Ponte, Ever Davila, Gloria Aguilar, Analı́a Porrás, Pilar Ramón-Pardo, José L. Castro, Daniela Guzmán, María Luisa Rioseco, Jaime Labarca, José Pablo Díaz Madriz, Josué Murillo Cubero, Allan Robles Calderón, Mónica Alfaro, Luisa Arias Soto, Alejandro Aayon, Tania Jiménez Oreamuno, Zulema Herrera Jiménez, Adriana Sequeira, Jorge Mederos Hernández, Jorge Luis Campistrous Lavaut, Damarys Castillo Meriño, Elsa Fleitas Ruisánchez, Damaris Portuondo Sánchez, Humberto Guanche Garcell, Juan José Pisonero Socías, Evelyn Perera Díaz, Norma America Cardoso Lunar, Irene Fiterre Lancís, José Antonio Ramírez, Midsay López Leyte, Ariadna Méndez Rosabal, Ebel Aldana Estrada, M. Bartolomé Cano, L. García Méndez, Anay Cordero Eiriz, Liana Padrón Menéndez, Gladys Fuentes Fernández, Raunel Reyes Ayala, Salomón Monroy, Ramón Menjívar, Carmen Elena Albanez Martínez, Diana Cabrera, Sofía Mercedes Menjivar Delgado, Gustavo Guzman, Rafael Jiménez-Mejía, Carolina Rodríguez, Sara Alvarenga, Mirian Alvarado, Ruth del Carmen Alvarado de Zelaya, Germán Bou, Guillermo Parada, Luis Cuéllar, Alexis Holguín, Yuan Almora Pinedo, Eduardo Sánchez Vergaray, Luis Enrique Vasquez Gil, Bertha Gizel Injante Ibazeta, Esther Dina Guadalupe Ricra, Rony Estrada Segura, Coralith García Apac, Jennifer Cuadros Inga, Roger Hernández, Marie Vallejo Vigo, Cesar Mujica Cuba, Pierina Vilcapoma, Eddie Angles-Yanqui, Débora Rocío Mananita Terrones, Rosa Terán Robles, Cristhian Resurrección, Alfredo Chiappe-Gonzalez, Martha Antezana, Socorro Torres Zegarra, Miguel Villegas-Chiroque, Roberto Díaz-Sipión, Jorge Marko A. Benitez-Peche, Jorge Alave, Jhoselyn Laura Goytizolo Ruiz, Angélica María Hernández Fernández, José Antonio Flores Vargas, Javier Araujo, Francisco Javier Arriaga García, Zoila Cruz Rivera, Víctor Monroy Colín, Katia Bustamante Ríos, Jorge Israel Hernández Blanquel, Eduardo Arias de la Garza, Héctor Hernández Gutiérrez, Karla Johanna Banegas León, Hortencia Esther Peralta Lara, Carlos Baltodano Arias, Eduardo Alemán Garay, Gladys Estigarribia, Livio Mereles Menchaca, Natalia Luraschi Viré, Dasy Acuña, Edgar Giménez Caballero,

Patient Satisfaction in Healthcare

Abstract Background Point prevalence surveys (PPSs) on antibiotic use are useful for understanding different aspects related to prescription patterns in hospitals. Methods An adaptation of the WHO methodology for a PPS on antibiotic use was applied. Hospital wards were divided into medical (MED), surgical (SUR), ICUs, gynaecology and obstetrics (GO), high-risk (HR) and mixed wards (MIX). A web application (RedCap©) through a mobile device was used for data collection. Results Between December 2018 and August 2019, 5444 patients in 33 hospitals in five countries were included (10 hospitals in Cuba, 7 in Paraguay, 6 in El Salvador, 5 in Mexico and 5 in Peru). Of these patients, 54.6% received at least one antibiotic, with variations between and within hospitals and countries. Antibiotics were more frequently used in ICUs (67.2%), SUR (64.5%) and MED wards (54.2%), with 51.2% of antibiotics prescribed for community-acquired infections (CAIs), 22.9% for healthcare-associated infections (HAIs), 11.1% for surgical prophylaxis and 6.1% for unknown reasons. Adherence to guidelines was observed in 68.6% of cases (72.8% for CAIs, 72.4% for HAIs and 44.3% for prophylaxis). Third-generation cephalosporins were the class of antibiotics most frequently used (26.8%), followed by carbapenems (10.3%) and fluoroquinolones (8%). Targeted treatments were achieved in 17.3% of cases. Conclusions Antibiotic use was generally higher than that published in other studies. There is an urgent need to promote and strengthen the antimicrobial stewardship programmes in Latin America.