Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2
2021; American Association for the Advancement of Science; Volume: 7; Issue: 50 Linguagem: Inglês
10.1126/sciadv.abj6538
ISSN2375-2548
AutoresKristen A. Rodrigues, Sergio A. Rodriguez‐Aponte, Neil C. Dalvie, Jeong Hyun Lee, Wuhbet Abraham, Diane G. Carnathan, Luis Jiménez, Julia T. Ngo, Jason Y.H. Chang, Zeli Zhang, Jingyou Yu, Aiquan Chang, Catherine Nakao, Benjamin Goodwin, Christopher A. Naranjo, Libin Zhang, Murillo Silva, Dan H. Barouch, Guido Silvestri, Shane Crotty, J. Christopher Love, Darrell J. Irvine,
Tópico(s)Immune responses and vaccinations
ResumoCoanchoring a SARS-CoV-2 immunogen and molecular adjuvants to alum extends vaccine kinetics and amplifies humoral immunity.
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