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Facile synthesis and antibacterial activity of silver nanoparticles-modified graphene oxide hybrid material: the assessment, utilization, and anti-virus potentiality

2022; Elsevier BV; Volume: 23; Linguagem: Inglês

10.1016/j.mtchem.2021.100738

2468-5194

Nguyen Minh Dat, Doan Ba Thinh, Le Minh Huong, N.T. Tinh, Nguyen Thi Thuy Linh, Nguyễn Duy Hải, Nguyen Duc Viet, Nguyen Tien Dat, Mai Thanh Phong, Nguyễn Hữu Hiếu,

Carbon and Quantum Dots Applications

The present work reported the one-pot preparation of silver nanoparticles doped with graphene oxide ([email protected]), using glucose as an eco-friendly reducing agent. The effects of synthesis conditions on the introduction of AgNPs onto graphene oxide sheets were confirmed by modern analytical techniques and antibacterial assays. Results showed that the [email protected] sample prepared with glucose:AgNO3:GO mass ratio of 1:1:1 at 60 °C for 60 min exhibited an appropriate one for further studies with AgNPs sizing of 16.66 ± 3.73 nm. The [email protected] effectively inhibited the development of S. enterica, P. aeruginosa, and S. aureus with the 50 % inhibitory concentration at 14.5, 0.9, and 6.8 μg/mL, respectively. The simultaneous effects of [email protected] concentration, pH, interaction time, annealing temperature, and bacterial density on the antibacterial activity of [email protected] were also investigated by Plackett-Burman and Box-Behnken design. The optimal values deducing for [email protected] concentration, pH, and bacterial density were 40 μg/mL, 5.5, and 5.1 × 106 CFU/mL, respectively, which could impressively reach 99.99 % of S. enterica elimination in practice. The interaction time and annealing temperature implied a negligible effect on the antibacterial activity of [email protected] All results of the present study affirmed the future use of [email protected] not only as an efficient antibacterial agent but also potentially as a novel anti-virus method of treatment.