DunedinPACE, a DNA methylation biomarker of the pace of aging
2022; eLife Sciences Publications Ltd; Volume: 11; Linguagem: Inglês
10.7554/elife.73420
ISSN2050-084X
AutoresDaniel W. Belsky, Avshalom Caspi, David L. Corcoran, Karen Sugden, Richie Poulton, Louise Arseneault, Andrea Baccarelli, Kartik Chamarti, Xu Gao, Eilís Hannon, Hona Lee Harrington, Renate Houts, Meeraj Kothari, Dayoon Kwon, Jonathan Mill, Joel Schwartz, Pantel Vokonas, Cuicui Wang, Benjamin Williams, Terrie E. Moffitt,
Tópico(s)Palliative Care and End-of-Life Issues
ResumoMeasures to quantify changes in the pace of biological aging in response to intervention are needed to evaluate geroprotective interventions for humans. Previously, we showed that quantification of the pace of biological aging from a DNA-methylation blood test was possible (Belsky et al., 2020). Here, we report a next-generation DNA-methylation biomarker of Pace of Aging, DunedinPACE (for Pace of Aging Calculated from the Epigenome).
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