Cirrhotic Cardiomyopathy
2010; Elsevier BV; Volume: 56; Issue: 7 Linguagem: Inglês
10.1016/j.jacc.2009.12.075
ISSN1558-3597
AutoresEnrico Maria Zardi, Antonio Abbate, Domenico Maria Zardi, Aldo Dobrina, Domenico Paolo Emanuele Margiotta, Benjamin W. Van Tassel, Antonella Afeltra, Arun J. Sanyal,
Tópico(s)Organ Transplantation Techniques and Outcomes
ResumoCirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress but normal to increased cardiac output and contractility at rest. As many as 50% of cirrhotic patients undergoing liver transplantation show signs of cardiac dysfunction, and 7% to 21% of deaths after orthotopic liver transplantation result from overt heart failure. In this review, we critically evaluate the existing literature on the pathophysiology and clinical implications of cirrhotic cardiomyopathy.
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