Produção Nacional
Fitoterapia: toxicidade e desinformação
2021; Volume: 9; Issue: 3 Linguagem: Inglês
10.4322/2675-133x.2022.044
ISSN2675-133X
AutoresBruna Soares de Souza Lima, Larissa Martins de Sena, Williana de Paula, Kainne Gomes de Souza Santos, Maurício Hanani Pinho Coelho, Rauane Silva Pires,
Tópico(s)Hibiscus Plant Research Studies
ResumoThe use of plants for the treatment of diseases is an old practice and which continues to be present in society nowadays, a scenario proven by the policies implemented for the insertion of Phytotherapy in public health.However, medicinal plants can be toxic, considering their active ingredients, so this is a relevant issue, given the frequency and increase of its use, and the lack of knowledge, on the part of the population, about the dangers arising from the use irregular these compounds.For this reason, this work aims to describe the active principles of the main medicinal plants used in Brazil, understand the mechanism related to hepatotoxicity and present the adverse effects and risks of the indiscriminate use of these herbal medicines.This is a narrative study, carried out through access to the SciELO and PubMed databases, using the following keywords: Hibisco, Erva cidreira, Cavalinha, Sacaca, Chá verde, Kava-Kava, Porangaba, Valeriana, Unha de Gato, Poejo e Cáscara Sagrada, and association with liver injuries.The active principles of herbal medicines, mentioned above, are diverse, so they can be used for various purposes.However, the indiscriminate use of these compounds showed potential hepatotoxicity, since the liver is the organ responsible for the metabolism of xenobiotics.Given this, it is essential to promote greater dissemination of information about the use of herbal medicines to the population, as well as it is necessary to broaden the understanding of possible adverse effects, including health professionals themselves, to avoid complications resulting from maladministration.
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