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Worldwide Network for Blood and Marrow Transplantation (WBMT) recommendations for establishing a hematopoietic stem cell transplantation program in countries with limited resources (Part II): Clinical, technical and socio-economic considerations

2019; Elsevier BV; Volume: 13; Issue: 1 Linguagem: Inglês

10.1016/j.hemonc.2019.08.002

1658-3876

Mahmoud Aljurf, Daniel J. Weisdorf, Shahrukh K. Hashmi, Amr Nassar, Éliane Gluckman, Mohamad Mohty, Douglas Rizzo, Marcelo C. Pasquini, Mehdi Hamadani, Wael Saber, Parameswaran Hari, Mohamed A. Kharfan‐Dabaja, Navneet S. Majhail, Usama Gerges, Amir Ali Hamidieh, Fazal Hussain, Alaa Elhaddad, H. K. Mahmoud, Abdelghani Tbakhi, Tarek Ben Othman, Rose Marie Hamladji, Mohamed Amine Bekadja, Parvez Ahmed, Ali Bazarbachi, S. Adil, Salam Alkindi, Saleh Ladeb, David Dennison, Mahomed Patel, Peihua Lu, Asmae Quessar, Shinichiro Okamoto, Yoshiko Atsuta, Ayman Alhejazi, Mouhab Ayas, Syed Osman Ahmed, N Novitzky, Alok Srivastava, Adriana Seber, Hassan El‐Solh, Ardeshir Ghavamzadeh, Dennis L. Confer, Y Kodera, Hildegard Greinix, Jeff Szer, Mary M. Horowitz, Dietger Niederwieser,

Neutropenia and Cancer Infections

The development of hematopoietic stem cell transplantation (HSCT) programs can face significant challenges in most developing countries because such endeavors must compete with other government health care priorities, including the delivery of basic services. While this is may be a limiting factor, these countries should prioritize development of the needed expertise to offer state of the art treatments including transplantation, by providing financial, technological, legal, ethical and other needed support. This would prove beneficial in providing successful programs customized to the needs of their population, and potentially provide long-term costsavings by circumventing the need for their citizens to seek care abroad. Costs of establishing HSCT program and the costs of the HSCT procedure itself can be substantial barriers in developing countries. Additionally, socioeconomic factors intrinsic to specific countries can influence access to HSCT, patient eligibility for HSCT and timely utilization of HSCT center capabilities. This report describes recommendations from the Worldwide Network for Blood and Marrow Transplantation (WBMT) for establishing HSCT programs with a specific focus on developing countries, and identifies challenges and opportunities for providing this specialized procedure in the resource constrained setting.