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Medicinal plants with potential antihypertensive properties: emphasis on natural products from the Brazilian Cerrado

2022; INSTITUTO DE BOTANICA; Volume: 49; Linguagem: Inglês

10.1590/2236-8906-123/2020

2236-8906

Marcelo Antônio da Trindade, Fernanda Cardoso da Silva, Bruna Juber de Araújo, Janayne Luihan Silva, Thaise Gonçalves Araújo, Cristina Ribas Fürstenau,

Botanical Research and Applications

ABSTRACT Arterial hypertension is a worldwide public health problem and the search for new medicines is one of the biggest challenges for the treatment of this pathology. Secondary metabolites of plants exhibit pharmacological properties of great phyto therapeutic interest. Cerrado is one of the largest biomes in Brazil and research with Cerrado plants as therapeutic resources is of growing interest. Our objective was to compile data regarding the Cerrado plants that already have some of their active compounds described and may potentially be used to treat arterial hypertension. We concluded that flavonoids, tannins, steroids and saponins exhibit important properties to low blood pressure. Thus, the species from Cerrado Brazilian such as pau-paraíba (Simarouba versicolor), pau-santo (Kielmeyera coriacea), abiu-do-cerrado (Pouteria torta), guarandi (Calophyllum brasiliense), bacaba (Oenocarpus bacaba), puçá-amarelo (Mouriri elliptica), fava-de-anta (Dimorphandramollis), murici (Byrsonima crassifolia) and cereja-do-cerrado (Eugenia calycina) are strong candidates for future herbal studies in this field.