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BIBTEX RIS

Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa

2022; Microbiology Society; Volume: 103; Issue: 1 Linguagem: Inglês

10.1099/jgv.0.001709

ISSN

1465-2099

Autores

Edmilson Ferreira de Oliveira-Filho, Ianei de Oliveira Carneiro, Carlo Fischer, Arne Kühne, Ignacio Postigo-Hidalgo, Jorge Raimundo Lins Ribas, Peggy Schumann, Kathrin Nowak, Jan F. Gogarten, Xavier de Lamballerie, Filipe Dantas‐Torres, Eduardo Martins Netto, Carlos Roberto Franke, Emmanuel Couacy‐Hymann, Fabian H. Leendertz, Jan Felix Drexler,

Tópico(s)

Viral Infections and Vectors

Resumo

Decades after its discovery in East Africa, Zika virus (ZIKV) emerged in Brazil in 2013 and infected millions of people during intense urban transmission. Whether vertebrates other than humans are involved in ZIKV transmission cycles remained unclear. Here, we investigate the role of different animals as ZIKV reservoirs by testing 1723 sera of pets, peri-domestic animals and African non-human primates (NHP) sampled during 2013–2018 in Brazil and 2006–2016 in Côte d'Ivoire. Exhaustive neutralization testing substantiated co-circulation of multiple flaviviruses and failed to confirm ZIKV infection in pets or peri-domestic animals in Côte d'Ivoire ( n =259) and Brazil ( n =1416). In contrast, ZIKV seroprevalence was 22.2% (2/9, 95% CI, 2.8–60.1) in West African chimpanzees ( Pan troglodytes verus ) and 11.1% (1/9, 95% CI, 0.3–48.3) in king colobus ( Colobus polycomos ). Our results indicate that while NHP may represent ZIKV reservoirs in Africa, pets or peri-domestic animals likely do not play a role in ZIKV transmission cycles.

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