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THERAPY OF ENDOCRINE DISEASE: Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing’s syndrome: a systematic review and meta-analysis

2016; Oxford University Press; Volume: 175; Issue: 6 Linguagem: Inglês

10.1530/eje-16-0465

1479-683X

Irina Bancos, Fares Alahdab, Rachel Crowley, Vasileios Chortis, Danae A. Delivanis, Dana Erickson, Neena Natt, Massimo Terzolo, Wiebke Arlt, William F. Young, M. Hassan Murad,

Hormonal Regulation and Hypertension

Beneficial effects of adrenalectomy on cardiovascular risk factors in patients with subclinical Cushing's syndrome (SCS) are uncertain. We sought to conduct a systematic review and meta-analysis with the following objectives: (i) determine the effect of adrenalectomy compared with conservative management on cardiovascular risk factors in patients with SCS and (ii) compare the effect of adrenalectomy on cardiovascular risk factors in patients with SCS vs those with a nonfunctioning (NF) adrenal tumor.