Artigo Acesso aberto Produção Nacional Revisado por pares

Severe varicella in a child immunosuppressed with methotrexate

2022; Elsevier BV; Volume: 97; Issue: 2 Linguagem: Inglês

10.1016/j.abd.2020.10.017

ISSN

1806-4841

Autores

Letícia Oba Galvão, Carmélia Matos Santiago Reis, Natália Lima Alves, Elisa Scandiuzzi Maciel,

Tópico(s)

Autoimmune and Inflammatory Disorders Research

Resumo

Varicella is a common viral infection in childhood and usually has a benign evolution. However, the evolution can be severe in immunosuppressed children. Vaccination can prevent its occurrence and especially the development of severe and/or complicated cases. Methotrexate is a systemic therapeutic option for many inflammatory diseases, and its immunosuppressive action exposes its users to a higher susceptibility to infection. The present report describes a case of severe varicella infection in a child immunosuppressed with methotrexate.

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