Portal de Periódicos da CAPES

P157. Usefulness of, and factors influencing, the Ulcerative Colitis Endoscopic Index of Severity for the evaluation of short-term treatment response

2016; Oxford University Press; Volume: 10; Issue: suppl 1 Linguagem: Inglês

10.1093/ecco-jcc/jjw019.276

1876-4479

Hankil Lee, Jun Yong Park, Ho Kim, Kana Kawagishi, Kaoru Yokoyama, Kiyonori Kobayashi, E Kim, Byung Ik Jang, K Kim, E Kim, Soyoung Jeon, H Lee, Jun Heo, Yong‐Jae Lee,

Diverticular Disease and Complications

during a thromboembolic event.Thromboembolic events occurred in 5 (86%) of the 7 patients with thrombophilia, and 1 in a patient without thrombophilia.In addition, 4 ischaemic strokes, 1 central retinal artery thrombosis, 1 venous sinus thrombosis, 1 jugular venous thrombosis, and 1 transient ischaemic attack were recorded.In addition, 1 patient showed positive anti-β2 microglobulin antibody; 3 showed positive lupus anticoagulant with MTHFR C677T homozygosity; 1 MTHFR C677T homozygosity, 1 positive lupus anticoagulant with MTHFR C677T heterozygosity; and 1 with positive lupus anticoagulant and MTHFR A1298C and C677T heterozygosity.Amongst the patients with thromboembolic events, 5 had Crohn's disease and 1 ulcerative colitis.The average age was 45.6 years with an average disease-evolution time of 61.2 months.The average Harvey-Bradshaw score was 5.4, and Mayo score was 11.Average erythrocyte sedimentation rate was 23 mm, and C-reactive protein was 2.97 mg/dL.It was necessary to optimise therapeutic in 2 patients.Conclusions: In our study, most of the patients with IBD and thrombophilias presented a thromboembolic event.Thromboembolic events were more frequent in Crohn's disease, with highest clinical activity scores.