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Fabrication of alpha irradiation technique and study the impact of low alpha particles density on the lymphoblast cells of Leukemia blood samples

2022; Elsevier BV; Volume: 1031; Linguagem: Inglês

10.1016/j.nima.2022.166494

1872-9576

Asaad H. Ismail, Runas Y. Sola,

Effects of Radiation Exposure

Fabrication of alpha irradiation technique has been fabricated using CR-39 nuclear track detector, medical injection pin, and micro capillarity tubes. Optimum alpha irradiation parameters (time of irradiation and alpha energy) were used to study the impacts of the low density of accumulated alpha particles on the percentages of lymphoblast cells (Blast cells) for 20 leukemia blood samples. The results show that the fabricated cell irradiation collimator is given significant results to irradiate whole blood samples. Low alpha particle density corresponded with the short time of irradiation at the fixed alpha energy (E=4.5 MeV). The results of the blast cell irradiation approved that the accumulated alpha particles affected the percentage of blast cells depending on the time of irradiation. 20 sec of irradiation is sufficient to reduce low blast cells percentage (≤30 %) to half, and 40 sec is enough to reduce blast cell percentage to half for the cases that have more than 30 % to 60 % of blast cells. Percentage of blast cells reduced regarded to the accumulated density of alpha particles in a power relationship.