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High-grade anal intraepithelial neoplasia treated with endoscopic submucosal dissection: a case report

2022; Volume: 85; Issue: 1 Linguagem: Inglês

10.51821/85.1.8192

1784-3227

João Santos‐Antunes, Emanuel Dias, Rosa Coelho, Margarida Marques, Pedro Amoroso Canão, Jorge Lima de Magalhães, Guilherme Macedo,

Gastric Cancer Management and Outcomes

Anal intraepithelial neoplasia is a premalignant lesion for anal squamous cell carcinoma. Current treatment options, consisting of topical therapy and local ablative procedures with electrocautery or radiofrequency ablation, are effective although recurrence rates are high. Experience with endoscopic submucosal dissection for anal lesions is limited, with only a few cases of anal intraepithelial neoplasia and early anal squamous cell carcinoma. We present a 65-year-old woman with high-grade anal intraepithelial neoplasia successfully removed by endoscopic submucosal dissection with no complications or signs of recurrence after 5 months, suggesting that this technique could be a safe and effective approach for management of anal premalignant lesions.