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The Role and Potential of 18F-FDG PET/CT in Malignant Melanoma: Prognostication, Monitoring Response to Targeted and Immunotherapy, and Radiomics

2022; Multidisciplinary Digital Publishing Institute; Volume: 12; Issue: 4 Linguagem: Inglês

10.3390/diagnostics12040929

2075-4418

Luca Filippi, Francesco Bianconi, Orazio Schillaci, Angela Spanu, Barbara Palumbo,

Medical Imaging Techniques and Applications

Novel therapeutic approaches, consisting of immune check-point inhibitors (ICIs) and molecularly targeted therapy, have thoroughly changed the clinical management of malignant melanoma (MM), the most frequent and deadly skin cancer. Since only 30-40% of MM patients respond to ICIs, imaging biomarkers suitable for the pre-therapeutic stratification and response assessment are warmly welcome. In this scenario, positron emission computed tomography (PET/CT) with