Portal de Periódicos da CAPES

Use of wastewater surveillance for early detection of Alpha and Epsilon SARS-CoV-2 variants of concern and estimation of overall COVID-19 infection burden

2022; Elsevier BV; Volume: 835; Linguagem: Inglês

10.1016/j.scitotenv.2022.155410

1879-1026

Van Vo, Richard Tillett, Katerina Papp, Shirley Shen, Richard Gu, Andrew Gorzalski, Danielle Denise Siao, Rayma Markland, Ching-Lan Chang, Hayley Baker, Jingchun Chen, Martin Schiller, Walter Q. Betancourt, Erin Buttery, Mark Pandori, Michael A. Picker, Daniel Gerrity, Edwin C. Oh,

COVID-19 Clinical Research Studies

A decline in diagnostic testing for SARS-CoV-2 is expected to delay the tracking of COVID-19 variants of concern and interest in the United States. We hypothesize that wastewater surveillance programs provide an effective alternative for detecting emerging variants and assessing COVID-19 incidence, particularly when clinical surveillance is limited. Here, we analyzed SARS-CoV-2 RNA in wastewater from eight locations across Southern Nevada between March 2020 and April 2021. Trends in SARS-CoV-2 RNA concentrations (ranging from 4.3 log