Artigo Acesso aberto Revisado por pares

Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies

2022; Oxford University Press; Volume: 9; Issue: 6 Linguagem: Inglês

10.1093/ofid/ofac171

ISSN

2328-8957

Autores

Jane C. Figueiredo, Fred R. Hirsch, Lawrence H. Kushi, Wendy N. Nembhard, James M. Crawford, Nicholas J. Mantis, Laurel J. Finster, Noah Merin, Akil Merchant, Karen L. Reckamp, Gil Y. Melmed, Jonathan Braun, Dermot McGovern, Samir Parekh, Douglas A. Corley, Namvar Zohoori, Benjamin C. Amick, Ruofei Du, Peter K. Gregersen, Betty Diamond, Emanuela Taioli, Carlos A. Sariol, Ana M. Espino, Daniela Weiskopf, Alba Gifoni, James D. Brien, William Hanege, Marc Lipsitch, David A. Zidar, Ann Scheck McAlearney, Ania Wajnberg, Joshua LaBaer, Edwin Lewis, Raquel A. Binder, Ann M. Moormann, Catherine S. Forconi, Sarah Forrester, Jennifer Batista, John S. Schieffelin, Dongjoo Kim, Giulia Biancon, Jennifer VanOudenhove, Stephanie Halene, Rong Fan, Dan H. Barouch, Galit Alter, Swetha Pinninti, Suresh B. Boppana, Sunil Pati, Misty Latting, Andrew H. Karaba, John D. Roback, Rafick‐Pierre Sékaly, Andrew S. Neish, Ahnalee M. Brincks, Douglas A. Granger, Amy B. Karger, Bharat Thyagarajan, Stefani N. Thomas, Sabra L. Klein, Andrea L. Cox, Todd Lucas, C. Debra M. Furr‐Holden, Kent Key, Nicole M. Jones, Jens Wrammerr, Mehul S. Suthar, Serre Yu Wong, Natalie M. Bowman, Viviana Simon, Lynne D. Richardson, Russell B. McBride, Florian Krammer, Meenakshi Rana, Joshua L. Kennedy, Karl W. Boehme, J. Craig Forrest, Steve W. Granger, Christopher D. Heaney, Maria Knight Lapinski, Shannon M. Wallet, Ralph S. Baric, Luca Schifanella, Marcos López, Soledad Fernández, Eben Kenah, Ashish R. Panchal, William J. Britt, Iñaki Sanz, Madhav V. Dhodapkar, Rafi Ahmed, Luther A. Bartelt, Alena J. Markmann, Jessica T. Lin, Robert S. Hagan, Matthew C. Wolfgang, Jacek Skarbinski,

Tópico(s)

COVID-19 Impact on Reproduction

Resumo

Abstract Background Global efforts are needed to elucidate the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the underlying cause of coronavirus disease 2019 (COVID-19), including seroprevalence, risk factors, and long-term sequelae, as well as immune responses after vaccination across populations and the social dimensions of prevention and treatment strategies. Methods In the United States, the National Cancer Institute in partnership with the National Institute of Allergy and Infectious Diseases, established the SARS-CoV-2 Serological Sciences Network (SeroNet) as the nation’s largest coordinated effort to study coronavirus disease 2019. The network comprises multidisciplinary researchers bridging gaps and fostering collaborations among immunologists, epidemiologists, virologists, clinicians and clinical laboratories, social and behavioral scientists, policymakers, data scientists, and community members. In total, 49 institutions form the SeroNet consortium to study individuals with cancer, autoimmune disease, inflammatory bowel diseases, cardiovascular diseases, human immunodeficiency virus, transplant recipients, as well as otherwise healthy pregnant women, children, college students, and high-risk occupational workers (including healthcare workers and first responders). Results Several studies focus on underrepresented populations, including ethnic minorities and rural communities. To support integrative data analyses across SeroNet studies, efforts are underway to define common data elements for standardized serology measurements, cellular and molecular assays, self-reported data, treatment, and clinical outcomes. Conclusions In this paper, we discuss the overarching framework for SeroNet epidemiology studies, critical research questions under investigation, and data accessibility for the worldwide scientific community. Lessons learned will help inform preparedness and responsiveness to future emerging diseases.

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