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Effect of Structured, Moderate Exercise on Kidney Function Decline in Sedentary Older Adults

2022; American Medical Association; Volume: 182; Issue: 6 Linguagem: Inglês

10.1001/jamainternmed.2022.1449

2168-6114

Michael G. Shlipak, Anoop Sheshadri, Fang‐Chi Hsu, Shyh‐Huei Chen, Vasantha Jotwani, Gregory J. Tranah, Roger A. Fielding, Christine K. Liu, Joachim H. Ix, Steven G. Coca, Marco Pahor, Jack M. Guralnik, Christina Leeuwenburgh, Connie Caudle, Lauren Crump, Latonia Holmes, Jocelyn Leeuwenburgh, Ching-ju Lu, Michael E. Miller, Mark A. Espeland, Walter T. Ambrosius, William B. Applegate, Daniel P. Beavers, Robert P. Byington, Delilah Cook, Curt D. Furberg, Lea N. Harvin, Leora Henkin, John Hepler, Fang‐Chi Hsu, Laura Lovato, Wesley Roberson, Julia Rushing, Scott Rushing, Cynthia L. Stowe, Michael P. Walkup, Don Hire, W. Jack Rejeski, Jeffrey A. Katula, Peter H. Brubaker, Shannon L. Mihalko, Janine M. Jennings, Evan C. Hadley, S Romashkan, Kushang V. Patel, Denise E. Bonds, Mary Mcdermott, Bonnie Spring, Michelle E. Hauser, Diana Kerwin, Kathryn Domanchuk, Rex Graff, Alvito Rego, Timothy S. Church, Steven N. Blair, Valerie H. Myers, Ron Monce, Nathan E. Britt, Melissa Harris, Ami Parks McGucken, Ruben Rodarte, Heidi K. Millet, Catrine Tudor‐Locke, Ben P. Butitta, Sheletta G. Donatto, Shannon Cocreham, ­Abby C. King, Cynthia M. Castro, William L. Haskell, Randall S. Stafford, Leslie A. Pruitt, Kathy Berra, Veronica Yank, Roger A. Fielding, Miriam E. Nelson, Sara C. Folta, Edward M. Phillips, Christine K. Liu, Erica McDavitt, Kieran F. Reid, Dylan Kirn, Evan Pasha, Won S. Kim, Vince E. Beard, Eleni X. Tsiroyannis, Cynthia Hau, Todd M. Manini, Stephen D. Anton, Susan Nayfield, Thomas W. Buford, Michael Marsiske, Bhanuprasad Sandesara, Jeffrey D. Knaggs, Megan S. Lorow, William C. Marena, Irina Korytov, Holly L. Morris, Margo Fitch, Floris Singletary, Jackie Causer, Katie A. Radcliff, Anne B. Newman, Stephanie A. Studenski, Bret H. Goodpaster, Nancy W. Glynn, Óscar García, Neelesh K. Nadkarni, Kathy Williams, Mark A. Newman, Geroge Grove, Janet T. Bonk, Jennifer Rushing, Piera Kost, Diane G. Ives, Stephen B. Kritchevsky, Anthony P. Marsh, Tina E. Brinkley, Jamehl S Demons, Kaycee M. Sink, Kimberly Kennedy, Rachel Shertzer‐Skinner, Abbie P. Wrights, Rose Fries, Deborah Barr, Thomas M. Gill, Robert S. Axtell, Susan S. Kashaf, Nathalie de Rekeneire, Joanne M. McGloin, Karen C. Wu, Denise Shepard, Barbara Fennelly, Lynne Iannone, Raeleen Mautner, Theresa Sweeney Barnett, Sean N. Halpin, Matthew Brennan, Julie A. Bugaj, Maria Zenoni, Bridget M. Mignosa, Jeff D. Williamson, Hugh C. Hendrie, Stephen R. Rapp, Joe Verghese, Nancy Woolard, Mark A. Espeland, Janine Jennings, Valerie K. Wilson, Carl J. Pepine, Mario Ariet, Eileen Handberg, Daniel Deluca, James O. Hill, Anita Szady, Geoffrey Chupp, Gail M. Flynn, John Hankinson, Carlos A. Vaz Fragoso, Erik J. Groessl, Robert M. Kaplan,

Blood Pressure and Hypertension Studies

Observational evidence suggests that higher physical activity is associated with slower kidney function decline; however, to our knowledge, no large trial has evaluated whether activity and exercise can ameliorate kidney function decline in older adults.