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BIBTEX RIS

Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden

2022; Oxford University Press; Volume: 114; Issue: 8 Linguagem: Inglês

10.1093/jnci/djac087

ISSN

1460-2105

Autores

Aurélie AG Gabriel, Joshua Atkins, Ricardo Cortez Cardoso Penha, Karl Smith-Byrne, Valérie Gaborieau, Catherine Voegele, Behnoush Abedi‐Ardekani, Maja Milojevic, Robert Olaso, Vincent Meyer, Anne Boland, Jean‐François Deleuze, Давид Заридзе, Anush Mukeriya, Beata Świątkowska, Vladimí­r Janout, Miriam Schejbalová, Dana Mateș, Jelena Stojšić, Miodrag Ognjanovic, John S. Witte, Sara R. Rashkin, Linda Kachuri, Rayjean J. Hung, Siddhartha Kar, Paul Brennan, Anne-Sophie Sertier, Anthony Ferrari, Alain Viari, Mattias Johansson, Christopher I. Amos, Matthieu Foll, James McKay,

Tópico(s)

Epigenetics and DNA Methylation

Resumo

Germline genetic variation contributes to lung cancer (LC) susceptibility. Previous genome-wide association studies (GWAS) have implicated susceptibility loci involved in smoking behaviors and DNA repair genes, but further work is required to identify susceptibility variants.

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