Artigo Acesso aberto Revisado por pares

Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in People with Cystic Fibrosis: A Clinical Trial

2021; American Thoracic Society; Volume: 205; Issue: 5 Linguagem: Inglês

10.1164/rccm.202108-1986oc

ISSN

1535-4970

Autores

David P. Nichols, Alex Paynter, Sonya L. Heltshe, Scott H. Donaldson, Carla A. Frederick, Steven D. Freedman, Daniel Gelfond, Lucas R. Hoffman, Andrea Kelly, Michael R. Narkewicz, Jessica E. Pittman, Félix Ratjen, Margaret Rosenfeld, Scott D. Sagel, Sarah Jane Schwarzenberg, Pradeep K. Singh, George M. Solomon, Michael S. Stalvey, John Clancy, Shannon Kirby, Jill M. Van Dalfsen, Margaret Kloster, Steven M. Rowe,

Tópico(s)

Nematode management and characterization studies

Resumo

The cystic fibrosis (CF) modulator drug, elexacaftor/tezacaftor/ivacaftor (ETI), proved highly effective in controlled clinical trials for individuals with at least one F508del allele, which occurs in at least 85% of people with CF.

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