Artigo Acesso aberto Revisado por pares

Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane

2021; American Society for Microbiology; Volume: 12; Issue: 6 Linguagem: Inglês

10.1128/mbio.00260-21

ISSN

2161-2129

Autores

Alicja M. Cygan, Pierre M. Jean Beltran, Alma G. Mendoza, Tess C. Branon, Alice Y. Ting, Steven A. Carr, John C. Boothroyd,

Tópico(s)

Mosquito-borne diseases and control

Resumo

Toxoplasma is an intracellular pathogen which resides and replicates inside a membrane-bound vacuole in infected cells. This vacuole is modified by both parasite and host proteins which participate in a variety of host-parasite interactions at this interface, including nutrient exchange, effector transport, and immune modulation.

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