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Duration of Protection against Mild and Severe Disease by Covid-19 Vaccines

2022; Massachusetts Medical Society; Volume: 386; Issue: 4 Linguagem: Inglês

10.1056/nejmoa2115481

1533-4406

Nick Andrews, Elise Tessier, Julia Stowe, Charlotte Gower, Freja Kirsebom, Ruth Simmons, Eileen Gallagher, Simon Thelwall, Natalie Groves, Gavin Dabrera, Richard Myers, Colin Campbell, Gayatri Amirthalingam, Matt Edmunds, Maria Zambon, Kevin Brown, Susan Hopkins, Meera Chand, Shamez Ladhani, Mary Ramsay, Jamie Lopez Bernal,

COVID-19 Clinical Research Studies

Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), have been used since December 2020 in the United Kingdom. Real-world data have shown the vaccines to be highly effective against Covid-19 and related severe disease and death. Vaccine effectiveness may wane over time since the receipt of the second dose of the ChAdOx1-S (ChAdOx1 nCoV-19) and BNT162b2 vaccines.