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Italian adaptation of EuroGuiDerm guideline on the systemic treatment of chronic plaque psoriasis

2022; Volume: 157; Linguagem: Inglês

10.23736/s2784-8671.21.07132-2

2784-8450

Paolo Gisondi, Maria Concetta Fargnoli, Paolo Amerio, Giuseppe Argenziano, Federico Bardazzi, Luca Bianchi, Andrea Chiricozzi, Andrea Conti, Monica Corazza, Antonio Costanzo, Paolo Dapavo, Clara De Simone, Gabriella Fabbrocini, Claudio Feliciani, Caterina Foti, Giampiero Girolomoni, Claudio Guarneri, Angelo Valerio Marzano, Giuseppe Micali, Annamaria Offidani, Aurora Parodi, Giovanni Pellacani, Stefano Piaserico, Francesca Prignano, Marco Romanelli, Franco Rongioletti, Pietro Rubegni, Giuseppe Stinco, Luca Stingeni, Carlo Tomasini, Marina Venturini, Ketty Peris, Piergiacomo Calzavara‐Pinton,

Sarcoidosis and Beryllium Toxicity Research

SIDeMaST (Società Italiana di Dermatologia Medica, Chirurgica, Estetica e delle Malattie Sessualmente Trasmesse) contributed to the development of the present guideline on the systemic treatment of chronic plaque psoriasis. With the permission of EuroGuiDerm, SIDeMaST adapted the guideline to the Italian healthcare context to supply a reliable and affordable tool to Italian physicians who take care of patients affected by moderate to severe plaque psoriasis. The content of the guideline includes general information on the scope and purpose, health questions covered, target users and strength/limitations of the guideline, suggestions for disease severity grading and treatment goals. It presents the general treatment recommendations as well as detailed management and monitoring recommendations for the individual drugs including acitretin, cyclosporine, fumarates, methotrexate, adalimumab, apremilast, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, secukinumab, tildrakizumab and ustekinumab. Moreover, the guideline provides guidance for specific clinical situations such as patient with concomitant psoriatic arthritis, inflammatory bowel disease, a history of malignancies, a history of depression, diabetes, viral hepatitis, disease affecting the heart or the kidneys as well as concomitant neurological disease. Advice on how to screen for tuberculosis and recommendations on how to manage patients with a positive tuberculosis test result are given. It further covers treatment for pregnant women or those with childbearing potential. Information on vaccination, immunogenicity and systemic treatment during the COVID-19 pandemic is also provided.