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Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial

2021; Elsevier BV; Volume: 398; Issue: 10318 Linguagem: Inglês

10.1016/s0140-6736(21)02329-1

1474-547X

Rajeka Lazarus, Sarah Baos, Heike Cappel-Porter, Andrew Carson‐Stevens, Madeleine Clout, Lucy Culliford, Stevan R. Emmett, Joanna Garstang, Lukuman Gbadamoshi, Bassam Hallis, Rosie Harris, David W. Hutton, Nick Jacobsen, Katherine Joyce, R.M. Kaminski, Vincenzo Libri, Alexander Middleditch, Liz McCullagh, Ed Moran, Adrian Phillipson, Elizabeth Price, John Ryan, Russell Thirard, Rachel Todd, Matthew D. Snape, David Tucker, Rachel Williams, Jonathan S Nguyen-Van-Tam, Adam Finn, Chris Rogers, Kirsty Adams, Seema Alaee, Parvinder K. Aley, Emma Allum, Sally Anthony, Kate Ashton, Tanya Awal, L. Matt Barnett, Alison Barratt, Charlotte Barron, Holly E. Baum, Chloe Beard, Lorna Bennett, Samuel Bird, Sarah Bishop, Jess Bisset, Pritesh Bodalia, Jane Bowles, Catherine Bowyer, Kirstie Bradburn, Jonathan James Hyett Bray, Catherine Bressington, Matthew Brimfield, Lauren Broad, Pauline Brown, Ruth Brydon-Hill, Sharon Burge, David Carmichael, Gurjit Chohan, Tonia Clark, Adrianne Close, Tom Coleman, Claire Cowley, Charlotte Cranfield, Eleanor R. Cross, Alyssa D'Agostino, Silvia D’Arcangelo, Ashley Otter, Kate Davies, Catrin Davies, R. W. DAVIES, Louisa Davies, Kimberley Driver, Charlotte Eglinton, Charlotte Ekblad, Emma Eldridge, Teriann Evans, Mim Evans, Isabel Evans, Yama F Mujadidi, A Farrow, Beverley Faulkner, Sally Feltham, Susan Figueirido, Jamie Ford, David A. Foxwell, Sharon Frayling, Sophie Gardiner, Karen E. Gooch, Jayne Goodwin, Alice Halliday, Shama Hamal, Sarah Harrhy, Andrew R. Harris, Lesley Haxton, Matthew Haynes, M. Hazell, Tracey Hembrough, Jacqueline Hewson, Bethany Hicks, Thomas F. Higgins, Michelle L. Hill, Alex Hills, N. Zoe Hilton, Benjamin Hitchings, Cheryl Hua, Hina Iftikhar, Attya Iqbal, Laura Jones, Nicola Jones, Johanna Kellett Wright, Sarah Kidd, Alison Kirby, Lucy Knibbs, Jenny Lamb, Helen Langton, Rwth Leach, Phoebe Lewis-Clarke, Amy Lloyd, Kirsty Maclean, Nicola Manning, Anthony C. Marriott, Isobel Joy McFadzean, Maeve McLaughlin, Alison McQueen, Bianca Mills, Gurudutt Naik, Lisa Nicholls, Chris Norman, Keren Northcott, Kerry Nyland, Catherine Oliver, Elizabeth Oliver, Jennifer Oliver, Diana Owen, Jemma Paterson, Lauren Pearce, Suzannah Pegler, Zoe Price, William B. Pynsent, Lidia Ramos, Tommy Rampling, David Rea, Karen Regan, Tawassal Riaz, Marivic Ricamara, Danielle Rice, Melody Rich, Marianne Roots, Kathryn A. Ryan, Yukari Sakagami, Ahmed Salem, Jade Salter-Hewitt, Michelle Samuels, Silvia Santoloce, Siwan Seaman, Michael Seneviratne, Sara Shankland, Louise Silva, Katie Smart, Rachel M. Smith, Joyce Smith, Rebecca E. Stringer, H. Keipp Talbot, Teresa Tarling, Sarah Taylor, Amy Thomas, Grace Tilzey, Gina Townley, Lisa Trembath, Kate Turkentine, Kelly Turner, Jenny Tyler, J Ugoji, Katharine Wale, Terrie Walker-Smith, Maggie Walton, Barbara Warnes, Sarah Whittley, Jennie Williams, Gail Williams, Kevin Williamson, Yee Ting Nicole Yim, Nicola Youlden,

Influenza Virus Research Studies

Concomitant administration of COVID-19 and influenza vaccines could reduce burden on health-care systems. We aimed to assess the safety of concomitant administration of ChAdOx1 or BNT162b2 plus an age-appropriate influenza vaccine.