Scientific Opinion on the safety and efficacy of l‐lysine sulphate produced by fermentation with Escherichia coli CGMCC 3705 for all animal species
2015; Wiley; Volume: 13; Issue: 7 Linguagem: Inglês
10.2903/j.efsa.2015.4155
ISSN1831-4732
Tópico(s)Genetically Modified Organisms Research
ResumoEFSA JournalVolume 13, Issue 7 4155 OpinionOpen Access Scientific Opinion on the safety and efficacy of L-lysine sulphate produced by fermentation with Escherichia coli CGMCC 3705 for all animal species EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Search for more papers by this author EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Search for more papers by this author First published: 06 July 2015 https://doi.org/10.2903/j.efsa.2015.4155Citations: 15 Panel members: Gabriele Aquilina, Vasileios Bampidis, Maria De Lourdes Bastos, Lucio Guido Costa, Gerhard Flachowsky, Mikolaj Antoni Gralak, Christer Hogstrand, Lubomir Leng, Secundino López-Puente, Giovanna Martelli, Baltasar Mayo, Fernando Ramos, Derek Renshaw, Guido Rychen, Maria Saarela, Kristen Sejrsen, Patrick Van Beelen, Robert John Wallace and Johannes Westendorf. Correspondence: FEEDAP@efsa.europa.eu Acknowledgement: The Panel wishes to thank the members of the Working Group on Amino Acids, including Paul Brantom, Noël Dierick and Jürgen Gropp, and the members of the Working Group on Genetically Modified Microorganisms, including Pier Sandro Cocconcelli, Boet Glandorf, Lieve Herman Sirpa Kärenlampi and Christoph Tebbe, for the preparatory work on this scientific opinion. Adoption date: 16 June 2015 Published date: 6 July 2015 Question number: EFSA-Q-2014-00003 On request from: European Commission Amended Date: 8 Feb 21 AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract The product L-lysine sulphate is a feed additive produced by fermentation with a genetically modified strain of Escherichia coli K-12. Neither the production strain nor its recombinant DNA was detected in the final product. Therefore, the product L-lysine sulphate, feed grade, manufactured by fermentation with E. coli CGMCC 3705, does not give rise to any safety concern with regard to the genetic modification of the production strain. Owing to potential adverse effects of the intrinsic high sulphate content in the product under application, a maximum supplementation of complete feed up to 1 % L-lysine sulphate is considered safe for all animal species and categories. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concludes that the use in animal feed of L-lysine sulphate produced by E. coli CGMCC 3705 does not pose a risk to the consumer or the environment. 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