Revisão Acesso aberto Revisado por pares

Alcohol Metabolism

2012; Elsevier BV; Volume: 16; Issue: 4 Linguagem: Inglês

10.1016/j.cld.2012.08.002

ISSN

1557-8224

Autores

Arthur I. Cederbaum,

Tópico(s)

Cannabis and Cannabinoid Research

Resumo

This article describes the pathways and factors that modulate blood alcohol levels and metabolism and describes how the body disposes of alcohol. The various factors that play a role in the distribution of alcohol in the body, influence the absorption of alcohol, and contribute to first-pass metabolism of alcohol are described. Most alcohol is oxidized in the liver, and general principles and overall mechanisms for alcohol oxidation are summarized. The kinetics of alcohol elimination in-vivo and the various genetic and environmental factors that can modify the rate of alcohol metabolism are discussed.

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