Glutethimide Intoxication
1971; American Medical Association; Volume: 215; Issue: 10 Linguagem: Inglês
10.1001/jama.1971.03180230076019
ISSN1538-3598
Autores Tópico(s)Pharmacogenetics and Drug Metabolism
ResumoTo the Editor.— Wright and Roscoe deserve congratulations for their initiative in helping to dispell the misconception that dialysis of some form is the treatment of choice for the patient who has received an overdose of glutethimide. Their communication, "Acute Glutethimide Poisoning: Conservative Management of 31 Patients" ( 214 :1704, 1970), illustrated that intensive supportive therapy alone yields satisfactory clinical results. The one death which occurred among the 31 cases reported was a patient who was grossly mismanaged in another hospital and died two hours after transfer to the Poisoning Treatment Center. Inclusion of this patient in the series of cases illustrating the results of treatment by intensive supportive care seems unjustified. It is suggested that this patient should be deleted from the series to be used as an example of the complications of mismanagement. With this modification their communication can be considered a report demonstrating 100% survival of a series
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