The Theory of the Gene
1917; University of Chicago Press; Volume: 51; Issue: 609 Linguagem: Inglês
10.1086/279629
ISSN1537-5323
Autores Tópico(s)Circular RNAs in diseases
ResumoNext article FreeThe Theory of the GeneT. H. MorganT. H. MorganPDFPDF PLUS Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinkedInRedditEmail SectionsMoreDetailsFiguresReferencesCited by The American Naturalist Volume 51, Number 609Sep., 1917 Published for The American Society of Naturalists Article DOIhttps://doi.org/10.1086/279629 Views: 2192Total views on this site Citations: 177Citations are reported from Crossref PDF download Crossref reports the following articles citing this article:Omnia Emam, Eman F. Wasfey, Nadia M. Hamdy Notch-associated lncRNAs profiling circuiting epigenetic modification in colorectal cancer, Cancer Cell International 22, no.11 (Oct 2022).https://doi.org/10.1186/s12935-022-02736-2Zhan Jing, Zhihui Liang, Liang Yang, Wenyan Du, Tao Yu, Huayu Tang, Changde Li, Wei Wei Bone formation and bone repair: The roles and crosstalk of osteoinductive signaling pathways, Process Biochemistry 118 (Jul 2022): 252–262.https://doi.org/10.1016/j.procbio.2022.04.033Yu Zhang, Qingzhong Liu, Yuanquan Shi MANAGE: A Novel Malware Evolution Model based on Digital Genes, (Jul 2022): 64–70.https://doi.org/10.1109/DSC55868.2022.00016Shuo Huang, George S. Deepe Notch regulates Histoplasma capsulatum clearance in mouse lungs during innate and adaptive immune response phases in primary infection, Journal of Leukocyte Biology 60 (May 2022).https://doi.org/10.1002/JLB.4A1221-743RFang-Shin Nian, Pei-Shan Hou Evolving Roles of Notch Signaling in Cortical Development, Frontiers in Neuroscience 16 (Mar 2022).https://doi.org/10.3389/fnins.2022.844410Daniel Láinez-González, Juana Serrano-López, Juan Manuel Alonso-Dominguez Understanding the Notch Signaling Pathway in Acute Myeloid Leukemia Stem Cells: From Hematopoiesis to Neoplasia, Cancers 14, no.66 (Mar 2022): 1459.https://doi.org/10.3390/cancers14061459Tetsuo Yasugi, Makoto Sato Mathematical modeling of Notch dynamics in Drosophila neural development, Fly 16, no.11 (Oct 2021): 24–36.https://doi.org/10.1080/19336934.2021.1953363Dongqing Mo, Jie Shen, Junzheng Zhang Use of FLP/FRT System to Screen for Notch Signaling Regulators in the Drosophila Wing, (Jun 2022): 39–48.https://doi.org/10.1007/978-1-0716-2201-8_4Huicong Li, Cheng Chang, Xueyu Li, Ruilin Zhang The roles and activation of endocardial Notch signaling in heart regeneration, Cell Regeneration 10, no.11 (Feb 2021).https://doi.org/10.1186/s13619-020-00060-6Sana Saleh, Mukhtar Ullah, Hammad Naveed Cell fate determination is influenced by Notch heterogeneity, (Nov 2021): 4143–4146.https://doi.org/10.1109/EMBC46164.2021.9629491Keith Baverstock The gene: An appraisal, Progress in Biophysics and Molecular Biology 164 (Sep 2021): 46–62.https://doi.org/10.1016/j.pbiomolbio.2021.04.005Anabel Martinez Lyons, Luke Boulter The developmental origins of Notch-driven intrahepatic bile duct disorders, Disease Models & Mechanisms 14, no.99 (Sep 2021).https://doi.org/10.1242/dmm.048413Pankaj Trivedi, Sandesh Kumar Patel, Diana Bellavia, Elena Messina, Rocco Palermo, Simona Ceccarelli, Cinzia Marchese, Eleni Anastasiadou, Lisa M. Minter, Maria Pia Felli When Viruses Cross Developmental Pathways, Frontiers in Cell and Developmental Biology 9 (Aug 2021).https://doi.org/10.3389/fcell.2021.691644Frederick Allen, Ivan Maillard Therapeutic Targeting of Notch Signaling: From Cancer to Inflammatory Disorders, Frontiers in Cell and Developmental Biology 9 (May 2021).https://doi.org/10.3389/fcell.2021.649205Hiroyuki Hosokawa, Kaori Masuhara, Maria Koizumi Transcription factors regulate early T cell development via redeployment of other factors, BioEssays 43, no.55 (Feb 2021): 2000345.https://doi.org/10.1002/bies.202000345Panagiotis F. Christopoulos, Torleif T. Gjølberg, Stig Krüger, Guttorm Haraldsen, Jan Terje Andersen, Eirik Sundlisæter Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases, Frontiers in Immunology 12 (Apr 2021).https://doi.org/10.3389/fimmu.2021.668207Wei Shen, Jiaxin Huang, Yan Wang Biological Significance of NOTCH Signaling Strength, Frontiers in Cell and Developmental Biology 9 (Mar 2021).https://doi.org/10.3389/fcell.2021.652273Ashley Vanderbeck, Ivan Maillard Notch signaling at the crossroads of innate and adaptive immunity, Journal of Leukocyte Biology 109, no.33 (Jun 2020): 535–548.https://doi.org/10.1002/JLB.1RI0520-138RWataru Saiki, Chenyu Ma, Tetsuya Okajima, Hideyuki Takeuchi Current Views on the Roles of O-Glycosylation in Controlling Notch-Ligand Interactions, Biomolecules 11, no.22 (Feb 2021): 309.https://doi.org/10.3390/biom11020309Tobias M. Ballhause, Shan Jiang, Anke Baranowsky, Sabine Brandt, Peter R. Mertens, Karl-Heinz Frosch, Timur Yorgan, Johannes Keller Relevance of Notch Signaling for Bone Metabolism and Regeneration, International Journal of Molecular Sciences 22, no.33 (Jan 2021): 1325.https://doi.org/10.3390/ijms22031325Samarpan Majumder, Judy S. Crabtree, Todd E. Golde, Lisa M. Minter, Barbara A. Osborne, Lucio Miele Targeting Notch in oncology: the path forward, Nature Reviews Drug Discovery 20, no.22 (Dec 2020): 125–144.https://doi.org/10.1038/s41573-020-00091-3Jörg Reichrath, Sandra Reichrath Notch Signaling in Prevention And Therapy: Fighting Cancer with a Two-Sided Sword, (Oct 2020): 1–7.https://doi.org/10.1007/978-3-030-55031-8_1Giulia Monticone, Lucio Miele Notch Pathway: A Journey from Notching Phenotypes to Cancer Immunotherapy, (Oct 2020): 201–222.https://doi.org/10.1007/978-3-030-55031-8_13Sylvain Provot, Ernestina Schipani, Joy Wu, Henry Kronenberg Development of the skeleton, (Jan 2021): 39–73.https://doi.org/10.1016/B978-0-12-813073-5.00003-4Mikhail Pakvasa, Pranav Haravu, Michael Boachie-Mensah, Alonzo Jones, Elam Coalson, Junyi Liao, Zongyue Zeng, Di Wu, Kevin Qin, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Fang He, Yukun Mao, Yongtao Zhang, Changchun Niu, Meng Wu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Michael J. Lee, Jennifer Moriatis Wolf, Aravind Athiviraham, Sherwin S. Ho, Tong-Chuan He, Kelly Hynes, Jason Strelzow, Mostafa El Dafrawy, Russell R. Reid Notch signaling: Its essential roles in bone and craniofacial development, Genes & Diseases 8, no.11 (Jan 2021): 8–24.https://doi.org/10.1016/j.gendis.2020.04.006Kazuyoshi Itoh, Shoko Nishihara Drosophila melanogaster in Glycobiology: Their Mutants Are Excellent Models for Human Diseases, (Jan 2021): 1–35.https://doi.org/10.1016/B978-0-12-819475-1.00043-2Alexandre Trindade, António Duarte Notch Signaling Function in the Angiocrine Regulation of Tumor Development, Cells 9, no.1111 (Nov 2020): 2467.https://doi.org/10.3390/cells9112467Luca Pagliaro, Claudia Sorrentino, Giovanni Roti Targeting Notch Trafficking and Processing in Cancers, Cells 9, no.1010 (Sep 2020): 2212.https://doi.org/10.3390/cells9102212Amnah Sharif, Ann Shaji, May Chammaa, Eileen Pawlik, Rodrigo Fernandez-Valdivia Notch Transduction in Non-Small Cell Lung Cancer, International Journal of Molecular Sciences 21, no.1616 (Aug 2020): 5691.https://doi.org/10.3390/ijms21165691Zeynep BAYRAMOĞLU, Betül ÜNAL, Sema Sezgin GÖKSU, Cumhur İ̇brahim BAŞSORGUN Evaluation of Notch1 gene expression in prostate carcinoma, Journal of Surgery and Medicine (Jun 2020).https://doi.org/10.28982/josam.680864Soyeon Shin, Kyungeun Kim, Hwa-Ryeon Kim, Kris Ylaya, Sung-Im Do, Stephen M. Hewitt, Hee-Sae Park, Jae-Seok Roe, Joon-Yong Chung, Jaewhan Song Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer, Cell Death & Differentiation 27, no.44 (Sep 2019): 1341–1354.https://doi.org/10.1038/s41418-019-0419-1Jilani Purusottapatnam Shaik, Ibrahim O. Alanazi, Akbar Ali Khan Pathan, Narasimha Reddy Parine, Majid A. Almadi, Nahla A. Azzam, Abdulrahman M. Aljebreen, Othman Alharbi, Mohammad Saud Alanazi, Zahid Khan Frequent Activation of Notch Signaling Pathway in Colorectal Cancers and Its Implication in Patient Survival Outcome, Journal of Oncology 2020 (Mar 2020): 1–8.https://doi.org/10.1155/2020/6768942Christopher A. Blackwood, Alessandro Bailetti, Sayan Nandi, Thomas Gridley, Jean M. Hébert Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice, Frontiers in Cell and Developmental Biology 8 (Feb 2020).https://doi.org/10.3389/fcell.2020.00113Jörg Reichrath, Sandra Reichrath Notch Signaling and Tissue Patterning in Embryology: An Introduction, (Feb 2020): 1–7.https://doi.org/10.1007/978-3-030-34436-8_1Jörg Reichrath, Sandra Reichrath Notch Signaling and Embryonic Development: An Ancient Friend, Revisited, (Feb 2020): 9–37.https://doi.org/10.1007/978-3-030-34436-8_2Sergio Córdoba, Carlos Estella Role of Notch Signaling in Leg Development in Drosophila melanogaster, (Feb 2020): 103–127.https://doi.org/10.1007/978-3-030-34436-8_7Jörg Reichrath, Sandra Reichrath Notch Pathway and Inherited Diseases: Challenge and Promise, (Feb 2020): 159–187.https://doi.org/10.1007/978-3-030-34436-8_9Jörg Reichrath, Sandra Reichrath A Snapshot of the Molecular Biology of Notch Signaling: Challenges and Promises, (Feb 2020): 1–7.https://doi.org/10.1007/978-3-030-36422-9_1Brendan McIntyre, Takayuki Asahara, Cantas Alev Overview of Basic Mechanisms of Notch Signaling in Development and Disease, (Feb 2020): 9–27.https://doi.org/10.1007/978-3-030-36422-9_2Rajaguru Aradhya, Krzysztof Jagla Insulin-dependent Non-canonical Activation of Notch in Drosophila: A Story of Notch-Induced Muscle Stem Cell Proliferation, (Feb 2020): 131–144.https://doi.org/10.1007/978-3-030-36422-9_9Joshua J. Breunig, Branden R. Nelson Notch and neural development, (Jan 2020): 285–310.https://doi.org/10.1016/B978-0-12-814405-3.00013-8G.Yu. Kudryavtsev, L.V. Kudryavtseva, L.M. Mikhaleva, N.A. Solovieva, I.I. Babichenko Immunohistochemical study of Ki-67, p53 and Notch1 expressions in prostate cancer of different grades, Arkhiv patologii 82, no.55 (Jan 2020): 42.https://doi.org/10.17116/patol20208205142Kathleen Donohue The Snail's Charm, The American Naturalist 193, no.22 (Dec 2018): 149–163.https://doi.org/10.1086/700960OJ Harrison, AC Visan, N Moorjani, A Modi, K Salhiyyah, C Torrens, S Ohri, FR Cagampang Defective NOTCH signaling drives increased vascular smooth muscle cell apoptosis and contractile differentiation in bicuspid aortic valve aortopathy: A review of the evidence and future directions, Trends in Cardiovascular Medicine 29, no.22 (Feb 2019): 61–68.https://doi.org/10.1016/j.tcm.2018.06.008 Bibliography, (Jan 2019): 489–533.https://doi.org/10.1016/B978-0-12-813635-5.16001-XSantiago Nahuel Villegas, Dolors Ferres-Marco, María Domínguez Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function, (Sep 2019): 15–35.https://doi.org/10.1007/978-3-030-23629-8_2Moritz Sander, Héctor Herranz MicroRNAs in Drosophila Cancer Models, (Sep 2019): 157–173.https://doi.org/10.1007/978-3-030-23629-8_9Caroline M. Nieberding, Gilles San Martin, Suzanne Saenko, Cerisse E. Allen, Paul M. Brakefield, Bertanne Visser Sexual selection contributes to partial restoration of phenotypic robustness in a butterfly, Scientific Reports 8, no.11 (Sep 2018).https://doi.org/10.1038/s41598-018-32132-8Rolake O. Alabi, Gregory Farber, Carl P. Blobel Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds, Physiological Reviews 98, no.44 (Oct 2018): 2025–2061.https://doi.org/10.1152/physrev.00029.2017Luming Ren, Dongqing Mo, Yunlong Li, Tong Liu, Huan Yin, Na Jiang, Junzheng Zhang, Edward Giniger A genetic mosaic screen identifies genes modulating Notch signaling in Drosophila, PLOS ONE 13, no.99 (Sep 2018): e0203781.https://doi.org/10.1371/journal.pone.0203781Elenaé Vázquez-Ulloa, Marcela Lizano, Marika Sjöqvist, Leslie Olmedo-Nieva, Adriana Contreras-Paredes Deregulation of the Notch pathway as a common road in viral carcinogenesis, Reviews in Medical Virology 28, no.55 (Jun 2018): e1988.https://doi.org/10.1002/rmv.1988Kenjiroo Matsumoto, Robert S. Haltiwanger What are the Real Functions of O-Glycan Modifications of Notch?, Trends in Glycoscience and Glycotechnology 30, no.175175 (Jul 2018): J103–J111.https://doi.org/10.4052/tigg.1720.4JGiulia Frezza, Mauro Capocci Thomas Hunt Morgan and the invisible gene: the right tool for the job, History and Philosophy of the Life Sciences 40, no.22 (Apr 2018).https://doi.org/10.1007/s40656-018-0196-zDaniel J. Lubin, Rosemarie Mick, Stuti G. Shroff, Kristen Stashek, Emma E. Furth The notch pathway is activated in neoplastic progression in esophageal squamous cell carcinoma, Human Pathology 72 (Feb 2018): 66–70.https://doi.org/10.1016/j.humpath.2017.11.004Richard Gawne, Kenneth Z. McKenna, H. Frederik Nijhout Unmodern Synthesis: Developmental Hierarchies and the Origin of Phenotypes, BioEssays 40, no.11 (Nov 2017): 1600265.https://doi.org/10.1002/bies.201600265Jyothi Vijayaraghavan, Barbara A. Osborne Noncanonical Notch Signaling, (Nov 2018): 35–53.https://doi.org/10.1007/978-1-4939-8859-4_2Benedetto Daniele Giaimo, Tilman Borggrefe , 1066 ( 2018): 3.https://doi.org/10.1007/978-3-319-89512-3_1Franz Oswald, Rhett A. Kovall , 1066 ( 2018): 279.https://doi.org/10.1007/978-3-319-89512-3_14G. Awong, J.C. Zúñiga-Pflücker Development of Human T Lymphocytes, (Jan 2018): 229–239.https://doi.org/10.1016/B978-0-08-100601-6.00115-0Musaddique Hussain, Chengyun Xu, Mashaal Ahmad, Youping Yang, Meiping Lu, Xiling Wu, Lanfang Tang, Ximei Wu Notch Signaling: Linking Embryonic Lung Development and Asthmatic Airway Remodeling, Molecular Pharmacology 92, no.66 (Oct 2017): 676–693.https://doi.org/10.1124/mol.117.110254Lei Liu, Wei Xiao Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia, BMC Ophthalmology 17, no.11 (Aug 2017).https://doi.org/10.1186/s12886-017-0532-1Tao Xu, Sung‐Soo Park, Benedetto Daniele Giaimo, Daniel Hall, Francesca Ferrante, Diana M Ho, Kazuya Hori, Lucas Anhezini, Iris Ertl, Marek Bartkuhn, Honglai Zhang, Eléna Milon, Kimberly Ha, Kevin P Conlon, Rork Kuick, Brandon Govindarajoo, Yang Zhang, Yuqing Sun, Yali Dou, Venkatesha Basrur, Kojo SJ Elenitoba‐Johnson, Alexey I Nesvizhskii, Julian Ceron, Cheng‐Yu Lee, Tilman Borggrefe, Rhett A Kovall, Jean‐François Rual RBPJ / CBF 1 interacts with L3 MBTL 3/ MBT 1 to promote repression of Notch signaling via histone demethylase KDM 1A/ LSD 1, The EMBO Journal 36, no.2121 (Oct 2017): 3232–3249.https://doi.org/10.15252/embj.201796525Jennifer DeCotiis, David Lukac KSHV and the Role of Notch Receptor Dysregulation in Disease Progression, Pathogens 6, no.33 (Aug 2017): 34.https://doi.org/10.3390/pathogens6030034Annie Park, Alfredo Ghezzi, Thilini P. Wijesekera, Nigel S. Atkinson Genetics and genomics of alcohol responses in Drosophila, Neuropharmacology 122 (Aug 2017): 22–35.https://doi.org/10.1016/j.neuropharm.2017.01.032Giulia Frezza Interaction: A case of "epistemological exaptation" in the life sciences, PARADIGMI , no.22 (Jul 2017): 191–206.https://doi.org/10.3280/PARA2017-002013Jan Mašek, Emma R. Andersson The developmental biology of genetic Notch disorders, Development 144, no.1010 (May 2017): 1743–1763.https://doi.org/10.1242/dev.148007Bo-Kai Liao, Andrew C. Oates Delta-Notch signalling in segmentation, Arthropod Structure & Development 46, no.33 (May 2017): 429–447.https://doi.org/10.1016/j.asd.2016.11.007Petter Portin, Adam Wilkins The Evolving Definition of the Term "Gene", Genetics 205, no.44 (Apr 2017): 1353–1364.https://doi.org/10.1534/genetics.116.196956Martin Baron Combining genetic and biophysical approaches to probe the structure and function relationships of the notch receptor, Molecular Membrane Biology 34, no.1-21-2 (Sep 2018): 33–49.https://doi.org/10.1080/09687688.2018.1503742M. Luisa Iruela-Arispe, Ann Zovein Angiogenesis, (Jan 2017): 85–89.e2.https://doi.org/10.1016/B978-0-323-35214-7.00008-1J.T. Baeten, B. Lilly Notch Signaling in Vascular Smooth Muscle Cells, (Jan 2017): 351–382.https://doi.org/10.1016/bs.apha.2016.07.002Wei Qin, Shiya Chen, Shasha Yang, Qian Xu, Chuanshan Xu, Jing Cai The Effect of Traditional Chinese Medicine on Neural Stem Cell Proliferation and Differentiation, Aging and disease 8, no.66 (Jan 2017): 792.https://doi.org/10.14336/AD.2017.0428Sten Friberg, Andreas M. Nyström NANOMEDICINE: will it offer possibilities to overcome multiple drug resistance in cancer?, Journal of Nanobiotechnology 14, no.11 (Mar 2016).https://doi.org/10.1186/s12951-016-0172-2Zhiyou Cai, Bin Zhao, Yanqing Deng, Shouqin Shangguan, Faming Zhou, Wenqing Zhou, Xiaoli Li, Yanfeng Li, Guanghui Chen Notch signaling in cerebrovascular diseases (Review), Molecular Medicine Reports (Aug 2016).https://doi.org/10.3892/mmr.2016.5641Robert Meunier Epistemic Competition between Developmental Biology and Genetics around 1900: Traditions, Concepts and Causation, NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin 24, no.22 (May 2016): 141–167.https://doi.org/10.1007/s00048-016-0143-6Guannan Zhu, Xiuli Yi, Sebastian Haferkamp, Sonja Hesbacher, Chunying Li, Matthias Goebeler, Tianwen Gao, Roland Houben, David Schrama Combination with γ-secretase inhibitor prolongs treatment efficacy of BRAF inhibitor in BRAF-mutated melanoma cells, Cancer Letters 376, no.11 (Jun 2016): 43–52.https://doi.org/10.1016/j.canlet.2016.03.028Yisu Gu, Massimo Masiero, Alison H. Banham Notch signaling: its roles and therapeutic potential in hematological malignancies, Oncotarget 7, no.2020 (Feb 2016): 29804–29823.https://doi.org/10.18632/oncotarget.7772Gang Deng, Libin Ma, Qi Meng, Xiang Ju, Kang Jiang, Peiwu Jiang, Zhijian Yu Notch signaling in the prostate: critical roles during development and in the hallmarks of prostate cancer biology, Journal of Cancer Research and Clinical Oncology 142, no.33 (Mar 2015): 531–547.https://doi.org/10.1007/s00432-015-1946-xMatthew J. Moulton, Anthea Letsou Modeling congenital disease and inborn errors of development in Drosophila melanogaster, Disease Models & Mechanisms 9, no.33 (Mar 2016): 253–269.https://doi.org/10.1242/dmm.023564Ciara N. Magee, Leonardo V. Riella Notch and its ligands in alloimmunity and rejection, Current Opinion in Organ Transplantation 21, no.11 (Feb 2016): 15–21.https://doi.org/10.1097/MOT.0000000000000266Morgan Taylor, Robert L. Coleman, Anil K. Sood The Role of Angiogenesis in Cancer, (Oct 2015): 64–71.https://doi.org/10.1002/9781118468678.ch6Charles Ambrose Muscle weakness during aging: a deficiency state involving declining angiogenesis, Ageing Research Reviews 23 (Sep 2015): 139–153.https://doi.org/10.1016/j.arr.2015.03.005Sonja Rothweiler, David Semela Notch pathway, (Aug 2015): 275–286.https://doi.org/10.1002/9781118663387.ch20Teri Hatzihristidis, Nikita Desai, Andrew P. Hutchins, Tzu-Ching Meng, Michel L. Tremblay, Diego Miranda-Saavedra A Drosophila -centric view of protein tyrosine phosphatases, FEBS Letters 589, no.99 (Mar 2015): 951–966.https://doi.org/10.1016/j.febslet.2015.03.005Robert Lickliter, Hunter Honeycutt Biology, Development, and Human Systems, (Mar 2015): 1–46.https://doi.org/10.1002/9781118963418.childpsy105Xingting Guo, Jun Chen, Zhaohui Li, Rongwen Xi Signaling Pathways Regulating Stem Cells, (Sep 2015): 145–177.https://doi.org/10.1007/978-94-017-7273-0_6Bert Leuridan The Structure of Scientific Theories, Explanation, and Unification. A Causal–Structural Account, The British Journal for the Philosophy of Science 65, no.44 (Dec 2020): 717–771.https://doi.org/10.1093/bjps/axt015Huajiao Guo, Yi Lu, Jianhua Wang, Xia Liu, Evan T. Keller, Qian Liu, Qinghua Zhou, Jian Zhang Targeting the Notch signaling pathway in cancer therapeutics, Thoracic Cancer 5, no.66 (Oct 2014): 473–486.https://doi.org/10.1111/1759-7714.12143Xinxia Zhang, Yaoyao Shi, Yuanyuan Weng, Qian Lai, Taobo Luo, Jing Zhao, Guoping Ren, Wande Li, Hongyang Pan, Yuehai Ke, Wei Zhang, Qiang He, Qingqing Wang, Ren Zhou, Jose Angel Martinez Climent The Truncate Mutation of Notch2 Enhances Cell Proliferation through Activating the NF-κB Signal Pathway in the Diffuse Large B-Cell Lymphomas, PLoS ONE 9, no.1010 (Oct 2014): e108747.https://doi.org/10.1371/journal.pone.0108747Peter D Turnpenny Syndromes and Diseases Associated with the Notch Signalling Pathway, (Aug 2014).https://doi.org/10.1002/9780470015902.a0024870Wenyu Liu, Katherine M. Morgan, Sharon R. Pine Activation of the Notch1 Stem Cell Signaling Pathway during Routine Cell Line Subculture, Frontiers in Oncology 4 (Aug 2014).https://doi.org/10.3389/fonc.2014.00211Camille Lobry, Philmo Oh, Marc R. Mansour, A. Thomas Look, Iannis Aifantis Notch signaling: switching an oncogene to a tumor suppressor, Blood 123, no.1616 (Apr 2014): 2451–2459.https://doi.org/10.1182/blood-2013-08-355818Filippos Aravanopoulos Genomics of Trees, (Apr 2014).https://doi.org/10.1201/b16714-23Panagiotis Ntziachristos, Jing Shan Lim, Julien Sage, Iannis Aifantis From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling, Cancer Cell 25, no.33 (Mar 2014): 318–334.https://doi.org/10.1016/j.ccr.2014.02.018Gregory Carrier, Matthieu Garnier, Loïc Le Cunff, Gaël Bougaran, Ian Probert, Colomban De Vargas, Erwan Corre, Jean-Paul Cadoret, Bruno Saint-Jean, María Mar Abad-Grau Comparative Transcriptome of Wild Type and Selected Strains of the Microalgae Tisochrysis lutea Provides Insights into the Genetic Basis, Lipid Metabolism and the Life Cycle, PLoS ONE 9, no.11 (Jan 2014): e86889.https://doi.org/10.1371/journal.pone.0086889Shinya Yamamoto, Karen L. Schulze, Hugo J. Bellen Introduction to Notch Signaling, (Jun 2014): 1–14.https://doi.org/10.1007/978-1-4939-1139-4_1G. Awong, J.C. Zúñiga-Pflücker Development of Human T Lymphocytes, (Jan 2014).https://doi.org/10.1016/B978-0-12-801238-3.00115-XMADHURI G. S. AITHAL, NARAYANAPPA RAJESWARI Role of Notch signalling pathway in cancer and its association with DNA methylation, Journal of Genetics 92, no.33 (Nov 2013): 667–675.https://doi.org/10.1007/s12041-013-0284-5Christen L. Ebens, Ivan Maillard Notch signaling in hematopoietic cell transplantation and T cell alloimmunity, Blood Reviews 27, no.66 (Nov 2013): 269–277.https://doi.org/10.1016/j.blre.2013.08.001Marion Vorms Theorizing and Representational Practices in Classical Genetics, Biological Theory 7, no.44 (Jul 2012): 311–324.https://doi.org/10.1007/s13752-012-0055-1Freddy Radtke, H. Robson MacDonald, Fabienne Tacchini-Cottier Regulation of innate and adaptive immunity by Notch, Nature Reviews Immunology 13, no.66 (May 2013): 427–437.https://doi.org/10.1038/nri3445J.J. Breunig, B.R. Nelson Notch and Neural Development, (Jan 2013): 313–332.https://doi.org/10.1016/B978-0-12-397265-1.00070-8Sylvain Provot, Ernestina Schipani, Joy Y. Wu, Henry Kronenberg Development of the Skeleton, (Jan 2013): 97–126.https://doi.org/10.1016/B978-0-12-415853-5.00006-6MIN MENG, XIN-HAN ZHAO, QIAN NING, LEI HOU, GUO-HONG XIN, LI-FENG LIU Tumor stem cells: A new approach for tumor therapy (Review), Oncology Letters 4, no.22 (May 2012): 187–193.https://doi.org/10.3892/ol.2012.730Klaus Geissler, Otto Zach Pathways involved in Drosophila and human cancer development: the Notch, Hedgehog, Wingless, Runt, and Trithorax pathway, Annals of Hematology 91, no.55 (Mar 2012): 645–669.https://doi.org/10.1007/s00277-012-1435-0Peter Andersen, Hideki Uosaki, Lincoln T Shenje, Chulan Kwon Non-canonical Notch signaling: emerging role and mechanism, Trends in Cell Biology 22, no.55 (May 2012): 257–265.https://doi.org/10.1016/j.tcb.2012.02.003Anna Bigas, Lluis Espinosa Hematopoietic stem cells: to be or Notch to be, Blood 119, no.1414 (Apr 2012): 3226–3235.https://doi.org/10.1182/blood-2011-10-355826Julia Izrailit, Michael Reedijk Developmental pathways in breast cancer and breast tumor-initiating cells: Therapeutic implications, Cancer Letters 317, no.22 (Apr 2012): 115–126.https://doi.org/10.1016/j.canlet.2011.11.028Thao P. Dang Notch, Apoptosis and Cancer, (Jan 2012): 199–209.https://doi.org/10.1007/978-1-4614-0899-4_15Paolo Antonio Ascierto, Maria Libera Ascierto, Mariaelena Capone, Zendee Elaba, Michael J. Murphy, Giuseppe Palmieri Molecular Pathogenesis of Melanoma: Established and Novel Pathways, (Nov 2011): 19–37.https://doi.org/10.1007/978-1-60761-433-3_3Su-Ni Tang, Sharmila Shankar, Rakesh K. Srivastava Cross Talks Among Notch, Wnt, and Hedgehog Signaling Pathways Regulate Stem Cell Characteristics, (Dec 2011): 593–606.https://doi.org/10.1007/978-94-007-2801-1_27Vibhavari Sail, M. Kyle Hadden Notch Pathway Modulators as Anticancer Chemotherapeutics, (Jan 2012): 267–280.https://doi.org/10.1016/B978-0-12-396492-2.00018-7Armel Hervé Nwabo Kamdje, Mauro Krampera Notch signaling in acute lymphoblastic leukemia: any role for stromal microenvironment?, Blood 118, no.2525 (Dec 2011): 6506–6514.https://doi.org/10.1182/blood-2011-08-376061K V Pajcini, N A Speck, W S Pear Notch signaling in mammalian hematopoietic stem cells, Leukemia 25, no.1010 (Jun 2011): 1525–1532.https://doi.org/10.1038/leu.2011.127Thant S. Zhu, Mark A. Costello, Caroline E. Talsma, Callie G. Flack, Jessica G. Crowley, Lisa L. Hamm, Xiaobing He, Shawn L. Hervey-Jumper, Jason A. Heth, Karin M. Muraszko, Francesco DiMeco, Angelo L. Vescovi, Xing Fan Endothelial Cells Create a Stem Cell Niche in Glioblastoma by Providing NOTCH Ligands That Nurture Self-Renewal of Cancer Stem-Like Cells, Cancer Research 71, no.1818 (Sep 2011): 6061–6072.https://doi.org/10.1158/0008-5472.CAN-10-4269Jialing Li, Ingo Neumann, Ines Volkmer, Martin Sebastian Staege Down-regulation of achaete-scute complex homolog 1 (ASCL1) in neuroblastoma cells induces up-regulation of insulin-like growth factor 2 (IGF2), Molecular Biology Reports 38, no.33 (Sep 2010): 1515–1521.https://doi.org/10.1007/s11033-010-0259-zXiaoyu Li, Harald von Boehmer Notch Signaling in T-Cell Development and T-ALL, ISRN Hematology 2011 (Jan 2011): 1–9.https://doi.org/10.5402/2011/921706Jean Deutsch Pending Issues in Development and Phylogeny of Arthropods, (Jan 2011): 54–81.https://doi.org/10.1201/b10425-6Kenneth M. Weiss Seeing the forest through the gene-trees, Evolutionary Anthropology: Issues, News, and Reviews 19, no.66 (Jan 2011): 210–221.https://doi.org/10.1002/evan.20286 By Samuel M. Scheiner [email protected] Toward a Conceptual Framework for Biology Samuel M. Scheiner, The Quarterly Review of Biology 85, no.33 (Jul 2015): 293–318.https://doi.org/10.1086/655117Zhi-Dong Zhou, Udhaya Kumari, Zhi-Cheng Xiao, Eng-King Tan Notch as a molecular switch in neural stem cells, IUBMB Life 62, no.88 (Jul 2010): 618–623.https://doi.org/10.1002/iub.362Jianning Tao, Shan Chen, Brendan Lee Alteration of Notch signaling in skeletal development and disease, Annals of the New York Academy of Sciences 1192, no.11 (Apr 2010): 257–268.https://doi.org/10.1111/j.1749-6632.2009.05307.xAlejandro Gutierrez, A. Thomas Look Molecular Targeted Therapies in T-Cell Acute Lymphoblastic Leukemia, (Jun 2010): 19–30.https://doi.org/10.1007/978-0-387-69062-9_2Sylvain Provot, Ernestina Schipani, Joy Wu, Henry Kronenberg Development of the Skeleton, (Jan 2010): 203–231.https://doi.org/10.1016/B978-0-12-375098-3.50011-1Ute Koch, Freddy Radtke Notch Signaling in Solid Tumors, (Jan 2010): 411–455.https://doi.org/10.1016/S0070-2153(10)92013-9Freddy Radtke, Nicolas Fasnacht, H. Robson MacDonald Notch Signaling in the Immune System, Immunity 32, no.11 (Jan 2010): 14–27.https://doi.org/10.1016/j.immuni.2010.01.004Xing Fan, Leila Khaki, Thant S. Zhu, Mary E. Soules, Caroline E. Talsma, Naheed Gul, Cheryl Koh, Jiangyang Zhang, Yue-Ming Li, Jarek Maciaczyk, Guido Nikkhah, Francesco DiMeco, Sara Piccirillo, Angelo L. Vescovi, Charles G. Eberhart NOTCH Pathway Blockade Depletes CD133-Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts , Stem Cells 28, no.11 (Nov 2009): 5–16.https://doi.org/10.1002/stem.254Giuseppe Palmieri, Mariaelena Capone, Maria Libera Ascierto, Giusy Gentilcore, David F Stroncek, Milena Casula, Maria Cristina Sini, Marco Palla, Nicola Mozzillo, Paolo A Ascierto Main roads to melanoma, Journal of Translational Medicine 7, no.11 (Oct 2009).https://doi.org/10.1186/1479-5876-7-86William KF Tse, Birgit Eisenhaber, Steven HK Ho, Qimei Ng, Frank Eisenhaber, Yun-Jin Jiang Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development, BMC Genomics 10, no.11 (Dec 2009).https://doi.org/10.1186/1471-2164-10-637Ashley R Sandy, Ivan Maillard Notch signaling in the hematopoietic system, Expert Opinion on Biological Therapy 9, no.1111 (Sep 2009): 1383–1398.https://doi.org/10.1517/14712590903260777Anne V. Buchanan, Samuel Sholtis, Joan Richtsmeier, Kenneth M. Weiss What are genes "for" or where are traits "from"? What is the question?, BioEssays 31, no.22 (Feb 2009): 198–208.https://doi.org/10.1002/bies.200800133Kenneth M Weiss Tilting at Quixotic Trait Loci (QTL): An Evolutionary Perspective on Genetic Causation, Genetics 179, no.44 (Aug 2008): 1741–1756.https://doi.org/10.1534/genetics.108.094128Root Gorelick, Manfred D. Laubichler Genetic = Heritable (Genetic ≠ DNA), Biological Theory 3, no.11 (Mar 2015): 79–84.https://doi.org/10.1162/biot.2008.3.1.79SYLVAIN PROVOT, ERNESTINA SCHIPANI, JOY WU, HENRY KRONENBERG Development of the Skeleton, (Jan 2008): 241–269.https://doi.org/10.1016/B978-012370544-0.50012-4Michael J. Tolentino, Anthony P. Adamis, Joan W. Miller Angiogenic Factors and Inhibitors, (Jan 2008): 315–336.https://doi.org/10.1016/B978-1-4160-0016-7.50034-5Victoria Bolós, Joaquín Grego-Bessa, José Luis de la Pompa Notch Signaling in Development and Cancer, Endocrine Re
Referência(s)