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BIBTEX RIS

Evidence of Acute Ischemic Tissue Change in Transient Global Amnesia in Magnetic Resonance Imaging: Case Report and Literature Review

2005; Wiley; Volume: 15; Issue: 2 Linguagem: Inglês

10.1111/j.1552-6569.2005.tb00309.x

1552-6569

Marcelo Felix, Luiz Henrique Martins Castro, Antônio Carlos Martins Maia, Antônio José da Rocha,

Anesthesia and Neurotoxicity Research

Transient global amnesia is a benign syndrome of sudden-onset alteration of behavior with temporary dysfunction of anterograde and recent retrograde memory. Its neural substrates remain uncertain. Possible causes include ischemia, migraine, and epilepsy. The authors report a case of a 62-year-old man with a transient attack of memory disturbance, suggestive of transient global amnesia, in which magnetic resonance imaging performed 48 hours after onset showed left mesial temporal lobe signal changes on diffusion-weighted imaging and fluid-attenuated inversion recovery images. The findings and a literature review lend further support to the ischemic pathogenesis of transient global amnesia as a possible etiology, and underscore the role of diffusion-weighted imaging in the diagnosis of this condition.