Ichthyosiform erythroderma, hair shaft abnormalities, and mental and growth retardation. A new recessive disorder
1971; American Medical Association; Volume: 104; Issue: 1 Linguagem: Inglês
10.1001/archderm.104.1.4
ISSN1538-3652
Autores Tópico(s)RNA Research and Splicing
ResumoA new autosomal recessive disorder characterized by growth retardation, progeria-like appearance, mental deficiency, nonbullous congenital ichthyosiform erythroderma, and hair shaft defects consisting of pili torti and trichorrhexis nodosa-like lesions was found in three children of a Chinese family in Singapore. It is possible that this disease is closely related to other rare ectomesodermal disorders with congenital ichthyosis, hair shaft defects, and other congenital abnormalities, and a new classification of these conditions is therefore proposed.
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