Introduction
1972; Linguagem: Inglês
10.1007/978-3-642-80642-1_1
ISSN0077-1015
Autores Tópico(s)Global Maritime and Colonial Histories
ResumoThe credit for the discovery of the prostaglandins rightly belongs to the Swedish scientist, U. S. von Euler. It is true that other workers had observed pharmacological effects with semen and pro-static extracts which can now, with hindsight, be attributed to the presence of prostaglandins (for example Battez and Boulet, 1913; Kurzrok and Lieb, 1930; Cockrill, Miller and Kurzrok, 1935; Goldblatt, 1933, 1935), but it was von Euler (1934, 1935 a, 1936, 1939) who established beyond doubt that the active principle, which he named prostaglandin, belongs to a completely new group of naturally occurring substances; furthermore, it was at von Euler's suggestion that Professor Sune Bergström in 1947 took up the problem of prostaglandin purification. This led to the isolation of the first two prostaglandins in 1960 and so a vast new field of chemical, biological and clinical importance was opened up.
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