Meet the First Authors
2020; Lippincott Williams & Wilkins; Volume: 126; Issue: 2 Linguagem: Inglês
10.1161/res.0000000000000322
ISSN1524-4571
Tópico(s)Cardiac Fibrosis and Remodeling
ResumoHomeCirculation ResearchVol. 126, No. 2Meet the First Authors Free AccessIn BriefPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessIn BriefPDF/EPUBMeet the First Authors Originally published16 Jan 2020https://doi.org/10.1161/RES.0000000000000322Circulation Research. 2020;126:160–161is related toMonogenic and Polygenic Contributions to Atrial Fibrillation RiskmiRNA-Mediated Suppression of a Cardioprotective Cardiokine as a Novel Mechanism Exacerbating Post-MI Remodeling by Sleep Breathing DisordersMetabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate Biosynthesisis related toActivated Endothelial TGFβ1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1Loss of Endothelial FTO Antagonizes Obesity-Induced Metabolic and Vascular DysfunctionLoss of Endothelial Endoglin Promotes High-Output Heart Failure Through Peripheral Arteriovenous Shunting Driven by VEGF SignalingTGFβ Signaling and Defective Thrombus Resolution (p 162)Download figureDownload PowerPointDr Magdalena Ludmila Bochenek is a senior postdoctoral research associate with Dr Katrin Schäfer at the Department of Cardiology I and the Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz (Germany). She earned her MS in Medical Biochemistry from the University of Reims (France) and completed her PhD in 2009 in the laboratory of Dr Catherine Nobes at the University of Bristol (United Kingdom). It was at this time that she became interested in endothelial cell biology and angiogenesis. After earning her PhD, she joined Dr Ralf Adams in the Department of Tissue Morphogenesis at the Max-Planck-Institute in Münster, Germany, where she further worked on the role of novel candidate proteins in angiogenesis. In 2013, she joined Katrin Schäfer in Mainz and was awarded a CTH Virchow Fellowship to foster young academics in 2014. Her research focuses on endothelial-related processes leading to thrombus nonresolution, with strong bench-to-bed translational aspects. Outside the lab, she enjoys spending time with her family.ACC2 Deletion Prevents Aspartate Synthesis (p 182)Download figureDownload PowerPointDr Julia Ritterhoff is an Acting Instructor at the Mitochondria and Metabolism Center at the University of Washington (UW). After completing her PhD at the University of Heidelberg in Germany, Julia joined Dr Rong Tian’s laboratory in 2015. She is interested in understanding which factors contribute to cardiac disease progression, and especially how metabolic rewiring leads to different forms of cardiac growth. Intrigued by many metabolic questions, Julia plays a large role in project management and mentorship of junior lab members. When she is not chasing different metabolites in the lab, she chases after her kids who keep her grounded and make sure she doesn’t spend too much time at work. Julia thinks writing papers and grants is more fun than running experiments, and she is eager to run her own lab. She can be found on Twitter @JuliaRitterhoff.Genetic Basis of Atrial Fibrillation (p 200)Download figureDownload PowerPointDr Seung Hoan Choi is a postdoctoral associate in the laboratory of Drs Patrick Ellinor and Steven Lubitz in the Cardiovascular Disease Initiative at the Broad Institute of MIT and Harvard. He earned his PhD from the Department of Biostatistics at Boston University with research focused on statistical genetics. His long-term interests are developing and applying novel statistical methods to elucidate the genetic basis of complex diseases. To achieve this goal, he has been developing his analytic capabilities in genetics, statistics, and large-scale data processing. During his postdoctoral training, he has used this foundation to elucidate the genetic basis of a common and complex human disease, atrial fibrillation. When he is not in the lab, he enjoys spending time with his family and two young children.Download figureDownload PowerPointSean Jurgens is a medical student at the University of Amsterdam and a research intern at the Broad Institute of MIT and Harvard. Under the supervision of Drs Patrick Ellinor and Steven Lubitz, his research has focused on the genetic underpinnings of cardiac electrophysiology and arrhythmia in the general population. Sean earned his BS at the University of Amsterdam in 2018 and is currently working towards both an MD and an MS. Sean aspires to improve societal health by becoming a physician-scientist who can translate fundamental scientific findings to clinical utility. Outside of the lab, and the clinic, he enjoys fitness, karate, and attending musical performances ranging from classical to house music.Obstructive Sleep Apnea and Ischemic Heart Failure (p 212)Download figureDownload PowerPointDr Yunhui Du earned her MS in Molecular Biotechnology (2005) at the University of Sydney and PhD in Physiology (2012) at the Capital Medical University, China. She completed her postdoctoral training in Dr Xinliang Ma’s lab at Thomas Jefferson University’s Department of Emergency Medicine in 2015. Currently, she is an Assistant Investigator (Assistant Professor equivalent) at the Beijing Institute of Heart, Lung and Vascular Diseases, Beijing Anzhen Hospital. Her research focuses on uncovering novel signalling transduction pathways leading to increased cardiovascular disease in obstructive sleep apnea and diabetes. She hopes to identify novel strategies effective to reduce obstructive sleep apnea/diabetes-related cardiovascular complications. Outside of work, Dr Du enjoys spending time with family and likes to travel around the world.Endothelial FTO in Obesity (p 232)Download figureDownload PowerPointDr Nenja Krüger earned her BS in Molecular Cell Biology in Heidelberg and her MS in Molecular Medicine in Göttingen. During her Master’s studies, she became interested in cardiovascular biology, especially related to metabolism. For this reason, she decided to pursue her PhD in an international cardiovascular graduating program (IRTG 1902) between the University of Düsseldorf (Mentor, Ulrich Rüther) and the University of Virginia in Charlottesville (Mentor, Brant Isakson). During this time, she focused on obesity-associated diseases and vascular biology. Specifically, she analyzed the importance of endothelial cells in the complexity of obesity-induced hypertension and diabetes. The international PhD has provided multiple collaborations and colleagues. In her free time, she loves to cook and tries as many different international recipes as she can.Endoglin and High Output Heart Failure (p 243)Download figureDownload PowerPointDr Simon Tual-Chalot earned his PhD in Cardiovascular Physiology in 2011 from the University of Angers, France. Interested in pursuing a research career in cardiovascular biology, he earned a Marie Curie Intra-European Fellowship in 2013 to work with Dr Helen Arthur at Newcastle University on the cardioprotective role of endoglin. In 2015, he became a joint investigator on a British Heart Foundation grant and was awarded a “Young Investigator Award” from Cure HHT to continue investigations on how endothelial endoglin regulates cardiovascular integrity. Currently, Dr Tual-Chalot is deputy group leader in Dr Konstantinos Stellos’s lab (www.stelloslab.com) at Newcastle University working on endothelial epitranscriptomics and he is eager to become a driving force in tomorrow’s cardiovascular research. Outside research, he is a keen ultra-runner, has a very caring and supportive wife, and two wonderful daughters. He can be found on Twitter @SimonTualChalot. Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesMonogenic and Polygenic Contributions to Atrial Fibrillation RiskSeung Hoan Choi, et al. Circulation Research. 2020;126:200-209miRNA-Mediated Suppression of a Cardioprotective Cardiokine as a Novel Mechanism Exacerbating Post-MI Remodeling by Sleep Breathing DisordersYunhui Du, et al. Circulation Research. 2020;126:212-228Metabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate BiosynthesisJulia Ritterhoff, et al. Circulation Research. 2020;126:182-196Activated Endothelial TGFβ1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1Magdalena L. Bochenek, et al. Circulation Research. 2020;126:162-181Loss of Endothelial FTO Antagonizes Obesity-Induced Metabolic and Vascular DysfunctionNenja Krüger, et al. Circulation Research. 2020;126:232-242Loss of Endothelial Endoglin Promotes High-Output Heart Failure Through Peripheral Arteriovenous Shunting Driven by VEGF SignalingSimon Tual-Chalot, et al. Circulation Research. 2020;126:243-257 January 17, 2020Vol 126, Issue 2 Advertisement Article InformationMetrics © 2020 American Heart Association, Inc.https://doi.org/10.1161/RES.0000000000000322PMID: 31944921 Originally publishedJanuary 16, 2020 PDF download Advertisement
Referência(s)