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Basaloid follicular hamartoma: a histologic diagnosis with diverse clinical presentations

1993; American Medical Association; Volume: 129; Issue: 7 Linguagem: Inglês

10.1001/archderm.129.7.915

1538-3652

B. R. Nelson,

Oral and Maxillofacial Pathology

To the Editor.— Basaloid follicular hamartoma is a benign adnexal tumor characterized histologically by the presence of branching cords and thin strands of undifferentiated anastomosing, basaloid proliferations that are embedded in a fibrous stroma. It has been well described histologically, but there does not appear to be any specific clinical characteristics. We describe two distinctly different clinical presentations of histologically confirmed basaloid follicular hamartoma and review the previous literature. In addition, we report the occurrence of anodular basal cell carcinoma within ahamartomatous plaque on the neck of one of our patients. Report of Cases.—Case 1.— A 34-year-old white man presented with an enlarging 1-cm pearly nodule with a "birthmark" on the right side of his neck. Physical examination revealed a 10xl3-cm flesh-to-yellow plaque on the right side of the neck composed of multiple coalescent papules and scattered 1- to 2-mm milia (Fig 1). An excisional biopsy specimen of the new nodule was diagnostic for nodular basal cell carcinoma. Adjacent to the tumor were