Portal de Periódicos da CAPES

Cutaneous angiomyolipoma

1996; Wiley; Volume: 23; Issue: 4 Linguagem: Inglês

10.1111/j.1600-0560.1996.tb01311.x

1600-0560

J. Fernando Val‐Bernal, Conceptión Mira,

Tuberous Sclerosis Complex Research

Extrarenal angiomyolipomas are rare lesions. An angiomyolipoma located on the right ear lobe in a 49‐year‐old man is reported. Pathologic examination showed a well‐circumscribed subcutaneous nodule, 2 cm in diameter. The components of the tumor were confirmed by immunohistochemistry. Reactivity for HMB‐45 was negative. A review of the twelve published cases, including the present, reveals that the patients' age ranged from 33 to 77 years (mean 53.6); the male/female ratio was 11:1. The tumors were solitary, asymptomatic, noninvasive, located most commonly in acral skin or on the ear. The clinical impression is that of a cyst, a lipoma or a vascular tumor. Signs of tuberous sclerosis were absent in all cases. In contrast to the renal form, the cutaneous angiomyolipoma is a tumor differing in sex predominance, clinical associations, circumscription, solitariness, and HMB‐45 immunoreactivity. Distinction from other mesenchymal lesions depends on recognition of traditional histologic criteria.