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Modular Assembly of Glycoproteins: Towards the Synthesis of GlyCAM‐1 by Using Expressed Protein Ligation

2004; Wiley; Volume: 116; Issue: 11 Linguagem: Inglês

10.1002/ange.200352673

1521-3757

Derek Macmillan, Carolyn R. Bertozzi,

Peptidase Inhibition and Analysis

Angewandte ChemieVolume 116, Issue 11 p. 1379-1383 Zuschrift Modular Assembly of Glycoproteins: Towards the Synthesis of GlyCAM-1 by Using Expressed Protein Ligation† Derek Macmillan Dr., Derek Macmillan Dr. derek.macmillan@ed.ac.uk School of Chemistry, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh, EH9 3JJ (GB), Fax: (+44) 131 650 4743Search for more papers by this authorCarolyn R. Bertozzi Prof., Carolyn R. Bertozzi Prof. Center for New Directions in Organic Synthesis, Departments of Chemistry and Molecular and Cell Biology and Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USASearch for more papers by this author Derek Macmillan Dr., Derek Macmillan Dr. derek.macmillan@ed.ac.uk School of Chemistry, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh, EH9 3JJ (GB), Fax: (+44) 131 650 4743Search for more papers by this authorCarolyn R. Bertozzi Prof., Carolyn R. Bertozzi Prof. Center for New Directions in Organic Synthesis, Departments of Chemistry and Molecular and Cell Biology and Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USASearch for more papers by this author First published: 02 March 2004 https://doi.org/10.1002/ange.200352673Citations: 20 † The center for New Directions in Organic Synthesis is supported by Bristol–Myers Squibb as Sponsoring Member and Novartis as Supporting Member. The authors acknowledge financial support from The National Science Foundation and the BBSRC. Read the full textAboutPDF ToolsRequest permissionAdd to favorites ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Zucker, wem Zucker gebührt: Physiologisch relevante Glycoproteine mit Sacchariden an vorgegebenen Stellen, wie GlyCAM-1, können aus kleinen synthetischen und bakteriell abgeleiteten Fragmenten unter Verwendung der "Expressed-Protein-Ligation"-Methode hergestellt werden. Die Technik wurde zur Synthese der drei semisynthetischen GlyCAM-1-Varianten 1–3 angewendet (siehe Schema). Citing Literature Supporting Information Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2004/z52673_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume116, Issue11March 5, 2004Pages 1379-1383 This is the German version of Angewandte Chemie. Note for articles published since 1962: Do not cite this version alone. Take me to the International Edition version with citable page numbers, DOI, and citation export. We apologize for the inconvenience. RelatedInformation