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Uterine Rupture During Second-Trimester Abortion Associated With Misoprostol

2001; Lippincott Williams & Wilkins; Volume: 98; Issue: 5, Part 2 Linguagem: Inglês

10.1097/00006250-200111001-00037

1873-233X

Laura Berghahn, Dennis Christensen, Sabine Droste,

Maternal and fetal healthcare

In Brief BACKGROUND Misoprostol use is contraindicated in women at term with a history of a uterine scar. There are limited data regarding the use of this drug in the midtrimester. CASE A 23-year-old woman with two prior cesareans presented at 23 weeks' gestation for pregnancy termination by dilation and evacuation. She had laminariae placed the day before and was instructed to take 400 μg of misoprostol intravaginally at midnight, then 400 μg buccally at 6:00 AM the day of the procedure. During the evacuation, uterine rupture was diagnosed. She underwent emergency laparotomy, and the uterus was repaired. CONCLUSION Uterine rupture can occur when misoprostol is used in the second trimester in a woman with a uterine scar. A woman with two previous cesarean sections ruptured her uterus in the second trimester after misoprostol was used for cervical ripening.