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Introduction to Subgroup Analyses

2003; Springer Nature; Linguagem: Inglês

10.1007/0-387-21813-0_10

1431-8776

Advanced Causal Inference Techniques

AbstractThis is the first of three chapters that discusses the role and interpretation of subgroup analyses in clinical trials. Subgroup analysis in a clinical trial is the evaluation of the effect of the randomly allocated intervention within only a fraction of the patients in the entire research cohort. This chapter provides some general background on the issue of subgroup evaluation, and discusses some of the interpretative difficulties that occur during the assessment of the effect of therapy within subgroups.KeywordsNYHA ClassNondiabetic PatientSubgroup EffectSubgroup EvaluationSubgroup MembershipThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.