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Richter's syndrome: Utility of 18F-FDG PET/CT

2013; Elsevier BV; Volume: 32; Issue: 2 Linguagem: Espanhol

10.1016/j.remnie.2013.01.020

2253-8089

Ana Maria García Vicente, G.A. Jiménez Londoño, B. Hernández Ruiz, Á. Soriano Castrejón,

Acute Myeloid Leukemia Research

Richter's syndrome (RS) refers to transformation of the chronic lymphoid leukemia (CLL) to a diffuse large cell lymphoma. Prognosis of patients with RS is generally considered unfavorable. We present two cases of patients with history of CLL, who had an increased of the lymphadenopathy, with elevated lactate dehydrogenase (LDH) in serum and increased 18F-FDG uptake of the neck lymph nodes, with subsequent confirmation of RS by histology. El síndrome de Richter (SR) se refiere a la transformación de la leucemia linfática crónica (LLC) en linfoma difuso de célula grande. El pronóstico de los pacientes con SR es considerado generalmente desfavorable. Presentamos dos casos de pacientes con historia de LLC y aumento de las adenopatías, con elevación en suero de la lactato deshidrogenasa (LDH) e incremento de la captación de 18F-FDG a nivel de adenopatías cervicales con la confirmación histológica posterior de SR.