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Zinc‐Finger Proteins for Site‐Specific Protein Positioning on DNA‐Origami Structures

2012; Wiley; Volume: 124; Issue: 10 Linguagem: Inglês

10.1002/ange.201108199

1521-3757

Eiji Nakata, Fong Fong Liew, Chisana Uwatoko, Shigeki Kiyonaka, Yasuo Mori, Yousuke Katsuda, Masayuki Endo, Hiroshi Sugiyama, Takashi Morii,

RNA and protein synthesis mechanisms

Fingerzeig: Zinkfingerproteine sind Adaptoren, die Positionen in DNA-Origami-Strukturen ortsselektiv ansteuern. Zwei solche Adaptoren können spezifische Positionen in orthogonaler Weise ansteuern, was in Escherichia-coli-Lysat, das Fusionsproteine der Adaptoren enthielt, zum Aufbau der erwarteten Protein-DNA-Struktur angewendet wurde. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.