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DIETARY ACCUMULATION AND DEPURATION OF HYDROPHOBIC ORGANOCHLORINES: BIOACCUMULATION PARAMETERS AND THEIR RELATIONSHIP WITH THE OCTANOL/WATER PARTITION COEFFICIENT

1998; Wiley; Volume: 17; Issue: 5 Linguagem: Inglês

10.1897/1551-5028(1998)017 2.3.co;2

1552-8618

Aaron T. Fisk, Ross J. Norstrom, Chris D. Cymbalisty, Derek C. G. Muir,

Toxic Organic Pollutants Impact

Environmental Toxicology and ChemistryVolume 17, Issue 5 p. 951-961 Article Dietary accumulation and depuration of hydrophobic organochlorines: Bioaccumulation parameters and their relationship with the octanol/water partition coefficient Aaron T. Fisk, Aaron T. Fisk Department of Soil Science, University of Manitoba, Winnipeg, Manitoba R3T 2N2, CanadaSearch for more papers by this authorRoss J. Norstrom, Ross J. Norstrom National Wildlife Research Center, Environment Canada, 100 Gamelin Boulevard, Hull, Quebec K1A 0H3, CanadaSearch for more papers by this authorChris D. Cymbalisty, Chris D. Cymbalisty Freshwater Institute, Department of Fisheries and Oceans, 501 University Crescent, Winnipeg, Manitoba R3T 2N6, CanadaSearch for more papers by this authorDerek C.G. Muir, Corresponding Author Derek C.G. Muir [email protected] Freshwater Institute, Department of Fisheries and Oceans, 501 University Crescent, Winnipeg, Manitoba R3T 2N6, CanadaThe current address of D.C.G. Muir is National Water Research Institute, Environment Canada, 867 Lakeshore Road, Burlington, Ontario L7R 4A6, CanadaSearch for more papers by this author Aaron T. Fisk, Aaron T. Fisk Department of Soil Science, University of Manitoba, Winnipeg, Manitoba R3T 2N2, CanadaSearch for more papers by this authorRoss J. Norstrom, Ross J. Norstrom National Wildlife Research Center, Environment Canada, 100 Gamelin Boulevard, Hull, Quebec K1A 0H3, CanadaSearch for more papers by this authorChris D. Cymbalisty, Chris D. Cymbalisty Freshwater Institute, Department of Fisheries and Oceans, 501 University Crescent, Winnipeg, Manitoba R3T 2N6, CanadaSearch for more papers by this authorDerek C.G. Muir, Corresponding Author Derek C.G. Muir [email protected] Freshwater Institute, Department of Fisheries and Oceans, 501 University Crescent, Winnipeg, Manitoba R3T 2N6, CanadaThe current address of D.C.G. Muir is National Water Research Institute, Environment Canada, 867 Lakeshore Road, Burlington, Ontario L7R 4A6, CanadaSearch for more papers by this author First published: 09 February 2010 https://doi.org/10.1002/etc.5620170526Citations: 296Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Dietary accumulation of 23 hydrophobic organochlorines (OCs) by juvenile rainbow trout (Oncorhynchus mykiss) was studied with the objective of obtaining relationships between bioaccumulation parameters and the octanol/water partition coefficient (Kow). A wide range of OCs were used including 16 polychlorinated biphenyls (PCBs 18, 28, 44, 52, 66, 101, 105, 118, 128, 138, 153, 187, 189, 195, 206, and 209), hexachlorobenzene, mirex, tris(4-chlorophenyl)methane (TCPMe), tris(4-chlorophenyl)methanol (TCPMeOH), and three toxaphene congeners (Cl7-chlorobornane [CHB] [Hp-sed], Cl8-CHB [T2], and Cl9-CHB [T12]). Tris(4-chlorophenyl)methane (half-life [t1/2] = 65 d) was more persistent than TCPMeOH (t1/2 = 20 d), and TCPMe was not biotransformed to TCPMeOH by rainbow trout. Cl7-chlorobornane (t1/2 = 32 d) was more rapidly eliminated, and appears to be more readily metabolized, than Cl8-CHB (t1/2 = 43 d) and Cl9-CHB (t1/2 = 42 d). With the exception of TCPMeOH, Cl7-CHB, and PCB 18, all of the OCs had biomagnification factors (BMFs) >1, implying a potential to biomagnify. Half-lives had a significant curvilinear relationship with Kow (R2 = 0.85, p < 0.001), with a maximum t1/2 for OCs with log Kow ∼ 7.0. Decreasing t1/2 for OCs of log Kow > 7.0 may be related to slow kinetics of these super hydrophobic OCs and the short exposure phase, which results in insufficient time for the super hydrophobic OCs to reach slower clearing compartments of the rainbow trout. Assimilation efficiency was not as well described by Kow as by t1/2 and BMF, although a significant curvilinear relationship was observed (R2 = 0.53, p = 0.004). The BMF had a significant curvilinear relationship with log Kow (R2 = 0.84, p < 0.001). 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