Four benzodiazepine radioimmunoassays are described, the most sensitive of which can detect sub-therapeutic levels of bromazepam, chlordiazepoxide, clobazam, demoxepam, desalkylflurazepam, desmethyldiazepam, diazepam, flunitrazepam, lorazepam, medazepam, nitrazepam, oxazepam, prazepam, temazepam and triazolam. The standard curve for diazepam has a concentration range of 0–2·5 ng ml The assay is particularly applicable to blood samples of forensic interest that may be haemolysed or decomposing. …
1980; Oxford University Press; Volume: 32; Issue: 1 Linguagem: Inglês
10.1111/j.2042-7158.1980.tb13064.x
ISSN2042-7158
AutoresKatherine Robinson, Mary G Rutterford, Richard Smith,
Tópico(s)Schizophrenia research and treatment
ResumoAbstract Four benzodiazepine radioimmunoassays are described, the most sensitive of which can detect sub-therapeutic levels of bromazepam, chlordiazepoxide, clobazam, demoxepam, desalkylflurazepam, desmethyldiazepam, diazepam, flunitrazepam, lorazepam, medazepam, nitrazepam, oxazepam, prazepam, temazepam and triazolam. The standard curve for diazepam has a concentration range of 0–2·5 ng ml The assay is particularly applicable to blood samples of forensic interest that may be haemolysed or decomposing. A 75 μI sample is required. The antiserum and [3 H]flunitrazepam used are commercially available.
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