Efficiency and Fidelity in a Click‐Chemistry Route to Triazole Dendrimers by the Copper( I )‐Catalyzed Ligation of Azides and Alkynes
2004; Wiley; Volume: 116; Issue: 30 Linguagem: Alemão
10.1002/ange.200454078
ISSN1521-3757
AutoresPeng Wu, Alina K. Feldman, Anne K. Nugent, Craig J. Hawker, Arnulf Scheel, Brigitte Voit, Jeffrey Pyun, Jean M. J. Fréchet, K. Barry Sharpless, Valery V. Fokin,
Tópico(s)Synthesis and Characterization of Heterocyclic Compounds
ResumoAngewandte ChemieVolume 116, Issue 30 p. 4018-4022 Zuschrift Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes† Peng Wu, Peng Wu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this authorAlina K. Feldman, Alina K. Feldman Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this authorAnne K. Nugent, Anne K. Nugent IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310Search for more papers by this authorCraig J. Hawker Dr., Craig J. Hawker Dr. hawker@almaden.ibm.com IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310Search for more papers by this authorArnulf Scheel, Arnulf Scheel IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310 Institut für Polymerforschung Dresden e.V. Hohe Strasse 6, 01069 Dresden, GermanySearch for more papers by this authorBrigitte Voit Prof., Brigitte Voit Prof. Institut für Polymerforschung Dresden e.V. Hohe Strasse 6, 01069 Dresden, GermanySearch for more papers by this authorJeffrey Pyun Dr., Jeffrey Pyun Dr. IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310 University of California, Department of Chemistry and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USASearch for more papers by this authorJean M. J. Fréchet, Jean M. J. Fréchet University of California, Department of Chemistry and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USASearch for more papers by this authorK. Barry Sharpless Prof., K. Barry Sharpless Prof. sharples@scripps.edu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this authorValery V. Fokin Prof., Valery V. Fokin Prof. fokin@scripps.edu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this author Peng Wu, Peng Wu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this authorAlina K. Feldman, Alina K. Feldman Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this authorAnne K. Nugent, Anne K. Nugent IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310Search for more papers by this authorCraig J. Hawker Dr., Craig J. Hawker Dr. hawker@almaden.ibm.com IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310Search for more papers by this authorArnulf Scheel, Arnulf Scheel IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310 Institut für Polymerforschung Dresden e.V. Hohe Strasse 6, 01069 Dresden, GermanySearch for more papers by this authorBrigitte Voit Prof., Brigitte Voit Prof. Institut für Polymerforschung Dresden e.V. Hohe Strasse 6, 01069 Dresden, GermanySearch for more papers by this authorJeffrey Pyun Dr., Jeffrey Pyun Dr. IBM Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA, Fax: (+1) 408-927-3310 University of California, Department of Chemistry and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USASearch for more papers by this authorJean M. J. Fréchet, Jean M. J. Fréchet University of California, Department of Chemistry and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USASearch for more papers by this authorK. Barry Sharpless Prof., K. Barry Sharpless Prof. sharples@scripps.edu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this authorValery V. Fokin Prof., Valery V. Fokin Prof. fokin@scripps.edu Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-7562Search for more papers by this author First published: 20 July 2004 https://doi.org/10.1002/ange.200454078Citations: 182 † We thank the National Institute of General Medical Sciences, the National Institutes of Health (GM 28284), the National Science Foundation (CHE-9985553), the W. M. Keck Foundation, the Skaggs Institute for Chemical Biology, the MRSEC Program of the National Science Foundation (award no. DMR-0213618 for the Center for Polymeric Interfaces and Macromolecular Assemblies), the NIRT Program of the National Science Foundation (grant no. 0210247), IBM Corporation, DOE-BES, and NSF International/DAAD for financial support. We are also grateful to Prof. M. G. Finn for helpful discussions. Read the full textAboutPDF ToolsRequest permissionAdd to favorites ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Komponenten, die Klick machen: Eine Vielzahl unterschiedlicher Dendrimere (siehe Schema) wurde mit der im Titel beschriebenen Click-Chemie-Umwandlung nahezu quantitativ erhalten. In einigen Fällen war zur Reinigung der Produkte dieses hoch effizienten Aufbaus der Triazoleinheiten der Dendrimere nur eine Filtration oder Lösungsmittelextraktion erforderlich. Citing Literature Supporting Information Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2004/z54078_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume116, Issue30July 26, 2004Pages 4018-4022 This article also appears in:Zu Ehren von Barry Sharpless This is the German version of Angewandte Chemie. Note for articles published since 1962: Do not cite this version alone. Take me to the International Edition version with citable page numbers, DOI, and citation export. We apologize for the inconvenience. RelatedInformation
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