Portal de Periódicos da CAPES

Reconfiguração de um Serviço de Urgência Central Polivalente Face à Pandemia COVID-19

2020; Sociedade Portuguesa de Medicina Interna; Volume: 27; Issue: S Linguagem: Inglês

10.24950/rspmi/covid19/a.oliveira/s/2020

2183-9980

Anabela Oliveira,

COVID-19 epidemiological studies

Despite all that is recognized so far on the ongoing SARS-CoV-2 pandemic, many questions remain to be answered, particularly in what concerns pathogen interaction with the human host and whether or not the acquired immune response is protective against re-infection in the long-term.The spectrum of COVID-19 ranges from asymptomatic infections to progressive critical states, a direct upshot from the complex interplay between virus pathogenicity and host antiviral defense.This review focuses on the immunologic response and disarrangements underlying the SARS-CoV-2 pathophysiology, gathering the information not only from the lessons learnt from SARS and MERS-CoV epidemics but also from what is already known about SARS-CoV-2 to date.This knowledge is paramount from the standpoint of disease prevention and control as well as diagnostic pipeline and treatment.