Artigo Revisado por pares

Selective Platination of Modified Oligonucleotides and Duplex Cross‐Links

2006; Wiley; Volume: 118; Issue: 48 Linguagem: Inglês

10.1002/ange.200603128

ISSN

1521-3757

Autores

Berta Algueró, Jaime López de la Osa, Carlos González, Enrique Pedroso, Vicente Marchán, Anna Grandas,

Tópico(s)

RNA Interference and Gene Delivery

Resumo

Angewandte ChemieVolume 118, Issue 48 p. 8374-8377 Zuschrift Selective Platination of Modified Oligonucleotides and Duplex Cross-Links† Berta Algueró Dr., Berta Algueró Dr. Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this authorJaime López de la Osa, Jaime López de la Osa Instituto de Química Física Rocasolano, CSIC, Serrano 119, 28006 Madrid, SpainSearch for more papers by this authorCarlos González Dr., Carlos González Dr. Instituto de Química Física Rocasolano, CSIC, Serrano 119, 28006 Madrid, SpainSearch for more papers by this authorEnrique Pedroso Prof., Enrique Pedroso Prof. Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this authorVicente Marchán Dr., Vicente Marchán Dr. [email protected] Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this authorAnna Grandas Prof., Anna Grandas Prof. [email protected] Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this author Berta Algueró Dr., Berta Algueró Dr. Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this authorJaime López de la Osa, Jaime López de la Osa Instituto de Química Física Rocasolano, CSIC, Serrano 119, 28006 Madrid, SpainSearch for more papers by this authorCarlos González Dr., Carlos González Dr. Instituto de Química Física Rocasolano, CSIC, Serrano 119, 28006 Madrid, SpainSearch for more papers by this authorEnrique Pedroso Prof., Enrique Pedroso Prof. Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this authorVicente Marchán Dr., Vicente Marchán Dr. [email protected] Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this authorAnna Grandas Prof., Anna Grandas Prof. [email protected] Departament de Química Orgànica, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1–11, 08028 Barcelona, Spain, Fax: (+34) 93-339-7878Search for more papers by this author First published: 04 December 2006 https://doi.org/10.1002/ange.200603128Citations: 2 † This work was supported by funds from the Ministerio de Educación y Ciencia (grant no. CTQ2004-8275) and the Generalitat de Catalunya (grant no. 2005SGR-693 and Centre de Referència de Biotecnologia). Read the full textAboutPDF ToolsRequest permissionAdd to favorites ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract Strangstabilisierung: Selektiv vernetzte Duplexe konnten auf zwei Weisen erhalten werden: entweder durch Hybridisierungs-gestützte Umlagerung platinierter Oligonucleotide oder durch Tempern Thioether- und Imidazol-modifizierter Oligonucleotide und ihrer komplementären Ketten in Gegenwart von Transplatin (siehe Struktur). 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