Polyribosomes
1985; Springer Nature; Linguagem: Inglês
10.1007/978-3-642-82587-3_16
ISSN0937-8340
Autores Tópico(s)RNA and protein synthesis mechanisms
ResumoRibosomes convert the information encoded in the nucleotide sequence of mRNA into the amino acid sequence of a protein. The translational mechanism by which this occurs involves a number of biochemical reactions (Weeks 1981). Initially, ribosomal subunits and methionyl-tRNA bind to the mRNA (initiation). This is followed by sequential “reading” of nucleotide triplets and addition of the corresponding amino acids into a nascent polypeptide (elongation). After the ribosome traverses the protein-coding region of the mRNA, it reaches a “stop” codon, which directs release of the ribosome and discharge of the completed polypeptide (termination).
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