Contents: (Small 5/2017)
2017; Wiley; Volume: 13; Issue: 5 Linguagem: Inglês
10.1002/smll.201770028
ISSN1613-6829
Resumocover pictures Lab-On-ChipIn article number 1601691, Y. Zhang and G. Wittstock demonstrate a novel and powerful platform for manipulation of microdroplets based on controlling the adhesion work to a hydrophobic wire.The wire can be used to pick up, transport, and lay down droplets with volumes between picoliters to microliters, avoiding the sliding of droplets over chip surfaces. Tissue EngineeringIn article number 1602769, H. Yu, L. Liu, and co-workers demonstrate a Tetris-inspired approach to fabricate 3D heterogeneous microscale tissue from hydrogel building blocks.The investigated system combines optofluidic maskless lithography and optically induced dielectrophoresis (ODEP).The customized bio-microstructures in Tetris shapes are dynamically synthesized using an optofluidic maskless lithography system and then transferred to an optically induced electrokinetics (OEK) chip for manipulation and assembly. Tumor VisualizationAnaerobic Clostridium novyi-NT (C.novyi-NT) has proved to be effective for treating tumors.X-ray computed tomography (CT) image guided delivery of this strain of bacteria to tumors has several great advantages over previous methods.In article number 1602722, A. C. Larson, D.-H.Kim, and co-workers developed an approach to coat the surface of C. novyi-NT spores with gold nanoparticles for CT-guided bacteriolytic therapy.Branched gold nanoparticles-coated spores are successfully injected into a tumor site under CT image guidance.A strong anti-tumor effect was observed in the in vivo tumor model.
Referência(s)