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Steatocystoma Multiplex

1958; American Medical Association; Volume: 77; Issue: 5 Linguagem: Inglês

10.1001/archderm.1958.01560050022005

1538-3652

Bencel L. Schiff,

Hedgehog Signaling Pathway Studies

Steatocystoma multiplex is recognized as a clinical entity characterized by cystic lesions of various sizes which arise from the pilosebaceous apparatus. Mount 1 gives credit to Bosellini for the first description of the disorder, in 1898, under the title of multiple follicular cutaneous cysts. It has since been given a variety of names: sebocystomatosis, widespread trichosebaceous cystic nevus, 2-4 and hereditary epidermal polycystic disease. 5,6 We believe that steatocystoma multiplex is preferable. The tumors are semioval, hemispheric, or round and are covered by normal-appearing skin. They are attached to the overlying skin and are freely movable with it. The lesions are asymptomatic and when incised yield an odorless syrupy substance which has chemical properties between those of blood lipid and depot fat. 7 The tumors are usually widespread and located mainly where there is lanugo hair. They may, however, be limited to the scrotum. 8 The