Idiopathic Thrombocytopenic Purpura
1966; Massachusetts Medical Society; Volume: 274; Issue: 24 Linguagem: Inglês
10.1056/nejm196606162742406
ISSN1533-4406
Autores Tópico(s)Blood groups and transfusion
ResumoSymptomatic Immunologic Thrombocytopenic PurpuraAssociation with Virus DisordersProbably only chronic thrombocytopenic purpura is truly idiopathic. The acute form is often preceded by a "viral" infection, particularly the exanthematous infections of children, and may therefore have a clear etiology.Viruses have been associated with thrombocytopenia in various ways. Recent studies, including those of me and my co-workers,10, 78 have shown that human blood platelets contain large amounts of sialic acid (assumed to be the virus receptor) and that myxoviruses are adsorbed to and eluted from blood platelets. In this process of adsorption and elution blood platelets undergo severe morphologic changes and . . .
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