Peptide Amphiphile Supramolecular Nanostructures as a Targeted Therapy for Atherosclerosis
2019; Wiley; Volume: 19; Issue: 6 Linguagem: Inglês
10.1002/mabi.201970016
ISSN1616-5195
AutoresNeel A. Mansukhani, Erica B. Peters, Miranda So, Mazen Albaghdadi, Zheng Wang, Mark R. Karver, Tristan D. Clemons, Jeffrey P. Laux, Nick D. Tsihlis, Samuel I. Stupp, Melina R. Kibbe,
Tópico(s)Chemical Synthesis and Analysis
ResumoFront Cover: Plaque-targeting peptides and liver X receptor agonists self assemble to form amphipathic nanofibers. Upon intravenous injection, the nanofibers target atherosclerotic lesions and reduced plaque burden. These findings demonstrate the potential of supramolecular system applications in cardiovascular nanomedicine. This is reported by Neel A. Mansukhani, Erica B. Peters, Miranda M. So, Mazen S. Albaghdadi, Zheng Wang, Mark R. Karver, Tristan D. Clemons, Jeffrey P. Laux, Nick D. Tsihlis, Samuel I. Stupp, and Melina R. Kibbe in article 1900066.
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